| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Glycated hemoglobin is not enough: The role of glycemia risk index for glycemic control assessment in type 1 diabetes
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bin-Bin He, Zi-Zhu Liu, Ruo-Yao Xu, Li Fan, Rui Guo, Chao Deng, Yu-Ting Xie, Zhi-Guang Zhou and Xia Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Noncommunicable Chronic Diseases-National Science and Technology Major Project |
No. 2023ZD0508201 |
| National Key R and D Program of China |
No. 2022YFC2010100 |
| National Natural Science Foundation of China |
No. 82070812 |
| Natural Science Foundation of Hunan Province |
No. 2024JJ9049 |
| Natural Science Foundation of Hunan Province |
No. 2023JJ30762 |
| Natural Science Foundation of Hunan Province |
No. 2021JC0003 |
| Sinocare Diabetes Foundation |
No. 2020SD08 |
| National Clinical Research Center for Metabolic Diseases Clinical Diagnosis and Treatment Capacity Enhancement Program |
No. 2023ZLNL003 |
|
| Corresponding Author |
Xia Li, PhD, Professor, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. lixia@csu.edu.cn |
| Key Words |
Continuous glucose monitoring; Glycemia risk index; Glycated hemoglobin; Glycemic control assessment; Type 1 diabetes |
| Core Tip |
This study highlights the GRI as a comprehensive metric that captures the multidimensional aspects of glycemic control, effectively addressing the limitations of HbA1c in T1D. Analyzing 328 patients with T1D, GRI showed stronger correlations with TBR and CV than HbA1c, providing a more nuanced reflection of glycemic risks. Clustering of CGM data identified distinct glycemic control subgroups, demonstrating GRI's ability to differentiate varying risks of hypoglycemia, hyperglycemia, and glycemic variability. Integrating HbA1c with the GRI enables a more accurate and holistic assessment, optimizing glycemic management in patients with T1D. |
| Publish Date |
2025-06-13 11:47 |
| Citation |
<p>He BB, Liu ZZ, Xu RY, Fan L, Guo R, Deng C, Xie YT, Zhou ZG, Li X. Glycated hemoglobin is not enough: The role of glycemia risk index for glycemic control assessment in type 1 diabetes. <i>World J Diabetes</i> 2025; 16(6): 104024</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i6/104024.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i6.104024 |
