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12/2/2014 10:47:00 AM | Browse: 704 | Download: 647
Publication Name World Journal of Gastroenterology
Manuscript ID 10417
Country/Territory Australia
Received
2014-03-31 09:41
Peer-Review Started
2014-03-31 17:46
To Make the First Decision
2014-06-10 13:29
Return for Revision
2014-06-15 13:48
Revised
2014-06-26 14:33
Second Decision
2014-08-28 09:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-08-28 10:05
Articles in Press
2014-08-28 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-11-16 12:48
Publish the Manuscript Online
2014-12-02 10:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Topic Highlights
Article Title Mechanistic links between gut microbial community dynamics, microbial functions and metabolic health
Manuscript Source Invited Manuscript
All Author List Connie WY Ha, Yan Y Lam and Andrew J Holmes
Funding Agency and Grant Number
Corresponding author Andrew J Holmes, PhD, School of Molecular Bioscience and Charles Perkins Centre, The University of Sydney, Building D17, Johns Hopkins Drive, Camperdown, NSW 2006, Australia. andrew.holmes@sydney.edu.au
Keywords Microbiome; Dysbiosis; High fat diet; Bile; Intestinal mucosa; Microbe-associated molecular patterns; Short chain fatty acids; Immunomodulation; Enteroendocrine cells
Core Tip The development of dysbiosis is driven by multiple factors. These include selective pressures imposed on the microbial community by the diet composition and feedback effects that involve either diet-host interaction or diet-microbiome-host interaction. The role of microbial signals in dysbiosis is well established but the involvement of host feedback mechanisms in aberrant host-microbial interactions is an under-appreciated part of disease progression. New opportunities to intervene in diseases of dysbiosis can result from targeting these distinct processes. These include stimulation of the host ability to self-regulate and blocking of deleterious host responses.
Publish Date 2014-12-02 10:46
Citation Ha CWY, Lam YY, Holmes AJ. Mechanistic links between gut microbial community dynamics, microbial functions and metabolic health. World J Gastroenterol 2014; 20(44): 16498-16517
Url http://www.wjgnet.com/1007-9327/full/v20/i44/16498.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i44.16498
Full Article (PDF) WJG-20-16498.pdf
Full Article (Word) WJG-20-16498.doc
Manuscript File 10417-Review.docx
Answering Reviewers 10417-Answering reviewers.pdf
Copyright License Agreement 10417-Copyright assignment.pdf
Peer-review Report 10417-Peer review(s).pdf
Scientific Misconduct Check 10417-CrossCheck.jpg
Scientific Editor Work List 10417-Scientific editor work list.pdf