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Articles Published Processes
3/13/2025 10:11:00 AM | Browse: 24 | Download: 35
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Received |
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2024-12-12 07:27 |
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Peer-Review Started |
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2024-12-12 07:28 |
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To Make the First Decision |
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Return for Revision |
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2025-01-15 19:51 |
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Revised |
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2025-01-28 23:15 |
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Second Decision |
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2025-02-14 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-14 05:10 |
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Articles in Press |
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2025-02-14 05:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-27 06:11 |
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Publish the Manuscript Online |
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2025-03-13 10:11 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
Cholangiocarcinoma: The era of liquid biopsy
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Manuscript Source |
Invited Manuscript |
All Author List |
Evgenia Kotsifa, Francesca Saffioti and Vasileios K Mavroeidis |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Vasileios K Mavroeidis, Chief Physician, MD, Department of Transplant Surgery, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Bristol BS10 5NB, United Kingdom. vasileios.mavroeidis@nhs.net |
Key Words |
Biliary tract cancer; Circulating tumour cells; Cell free DNA; Circulating tumour DNA; Circulating RNA; Biomarkers; Extracellular vesicles; Precision medicine |
Core Tip |
Cholangiocarcinoma (CCA) is an aggressive and heterogeneous malignancy that presents significant challenges in early detection, prognostication and monitoring using current diagnostic methods. Liquid biopsy (LB) emerges as a promising non-invasive technique, leveraging circulating tumour cells, cell-free DNA, circulating tumour DNA, RNA and extracellular vesicles as biomarkers. This review highlights the potential of LB to transform CCA management by improving early diagnosis, providing better prognostic insights and enabling dynamic patient monitoring. While LB shows substantial promise, critical limitations remain, necessitating further research to validate and optimise its integration into precision oncology for CCA. |
Publish Date |
2025-03-13 10:11 |
Citation |
<p>Kotsifa E, Saffioti F, Mavroeidis VK. Cholangiocarcinoma: The era of liquid biopsy. <i>World J Gastroenterol</i> 2025; 31(11): 104170</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i11/104170.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i11.104170 |
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