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5/15/2025 10:28:50 AM | Browse: 22 | Download: 66
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 104172
Country China
Received
2024-12-27 08:29
Peer-Review Started
2024-12-27 08:29
To Make the First Decision
Return for Revision
2025-01-13 02:01
Revised
2025-01-20 14:16
Second Decision
2025-02-26 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-26 06:47
Articles in Press
2025-02-26 06:47
Publication Fee Transferred
2025-01-22 04:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-27 09:15
Publish the Manuscript Online
2025-05-15 10:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Prediction of Ki-67 expression in hepatocellular carcinoma with machine learning models based on intratumoral and peritumoral radiomic features
Manuscript Source Unsolicited Manuscript
All Author List Zi-Wei Zhu, Jun Wu, Yang Guo, Qiong-Yuan Ren, Dong-Ning Li, Ze-Yu Li and Lei Han
ORCID
Author(s) ORCID Number
Zi-Wei Zhu http://orcid.org/0009-0005-0795-7862
Lei Han http://orcid.org/0000-0002-9606-7837
Funding Agency and Grant Number
Funding Agency Grant Number
Joint Science and Technology Plan Project of Liaoning Province, China 2024JH2/102600291
Corresponding Author Lei Han, Associate Chief Physician, MD, Department of Hepatobiliary Surgery, The General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenyang 110016, Liaoning Province, China. hanlei1974@sina.com
Key Words Hepatocellular carcinoma; Ki-67; Computed tomography; Machine learning; Radiomics
Core Tip Ki-67 expression is significantly correlated with hepatocellular carcinoma prognosis, and preoperative prediction of Ki-67 expression is crucial. To date, scholars have used radiomic features of tumour regions to predict their expression but have overlooked the important role of the peritumoral region. The findings in this study indicate that machine learning models that fully utilize the features of radiomics, tumour surrounding areas, and clinical factors can more accurately predict Ki-67 expression in hepatocellular carcinoma, thereby helping to improve personalized treatment strategies for liver cancer patients.
Publish Date 2025-05-15 10:28
Citation <p>Zhu ZW, Wu J, Guo Y, Ren QY, Li DN, Li ZY, Han L. Prediction of Ki-67 expression in hepatocellular carcinoma with machine learning models based on intratumoral and peritumoral radiomic features. <i>World J Gastrointest Oncol</i> 2025; 17(5): 104172</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i5/104172.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i5.104172
Full Article (PDF) WJGO-17-104172-with-cover.pdf
Manuscript File 104172_Auto_Edited_075233.docx
Answering Reviewers 104172-answering-reviewers.pdf
Audio Core Tip 104172-audio.mp3
Biostatistics Review Certificate 104172-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 104172-conflict-of-interest-statement.pdf
Copyright License Agreement 104172-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 104172-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s) 104172-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 104172-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 104172-non-native-speakers.pdf
Supplementary Material 104172-supplementary-material.pdf
Peer-review Report 104172-peer-reviews.pdf
Scientific Misconduct Check 104172-scientific-misconduct-check.png
Scientific Editor Work List 104172-scientific-editor-work-list.pdf
CrossCheck Report 104172-crosscheck-report.pdf