ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Role of serological biomarkers in evaluating and predicting endoscopic activity in inflammatory bowel disease
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xue Liu, Lin-Xiao Pan, Jia-Xian Pei, Tian Pu, Hong-Tao Wen and Ye Zhao |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Henan Natural Science Foundation |
232300421181 |
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Corresponding Author |
Ye Zhao, Chief Physician, MD, Professor, Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Erqi District, Zhengzhou 450052, Henan Province, China. jamie006@126.com |
Key Words |
Inflammatory bowel disease; Ulcerative colitis; Crohn’s disease; Biomarkers; Endoscopic activity; Nomogram; Prediction model |
Core Tip |
This is a retrospective single-center observational study to examine the correlation of serum biomarkers with endoscopic activity of ulcerative colitis (UC) and Crohn’s disease (CD), evaluate their diagnostic significance, and develop nomogram models to forecast endoscopic activity. Many markers such as white blood cell, hemoglobin, hematocrit, platelet (PLT), neutrophil, C-reactive protein (CRP), erythrocyte sedimentation rate, albumin (ALB), globulin, ALB/globulin, CRP/ALB, CRP/lymphocyte, PLT/lymphocyte, PLT/ALB, and neutrophil/lymphocyte are associated with endoscopic activity in patients with UC and CD. We can predict endoscopic severity of UC and CD by using the nomogram models. |
Publish Date |
2025-05-13 08:31 |
Citation |
<p>Liu X, Pan LX, Pei JX, Pu T, Wen HT, Zhao Y. Role of serological biomarkers in evaluating and predicting endoscopic activity in inflammatory bowel disease. <i>World J Gastroenterol</i> 2025; 31(18): 104206</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i18/104206.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i18.104206 |