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6/11/2025 6:21:38 AM | Browse: 7 | Download: 0
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 104234
Country South Korea
Received
2024-12-16 08:18
Peer-Review Started
2024-12-16 08:19
To Make the First Decision
Return for Revision
2025-03-01 06:33
Revised
2025-03-29 05:00
Second Decision
2025-05-13 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-13 08:54
Articles in Press
2025-05-13 08:54
Publication Fee Transferred
2025-04-03 02:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-06-04 01:41
Publish the Manuscript Online
2025-06-11 06:21
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers
Manuscript Source Unsolicited Manuscript
All Author List Na Rae Lim and Woo Chul Chung
ORCID
Author(s) ORCID Number
Na Rae Lim http://orcid.org/0000-0002-8596-3054
Woo Chul Chung http://orcid.org/0000-0003-1044-0440
Funding Agency and Grant Number
Corresponding Author Woo Chul Chung, MD, PhD, Professor, Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University, Jungbu-daero 93, Seoul 16247, South Korea. jwchulkr@catholic.ac.kr
Key Words Peptic ulcer; Bleeding; Proton pump inhibitor; Potassium competitive acid blocker; Ulcer bleeding
Core Tip This study compared the effectiveness of intravenous proton pump inhibitors (PPIs) and oral potassium competitive acid blockers (PCABs) in managing non-variceal upper gastrointestinal bleeding prior to emergency endoscopy. PPI injection and PCAB administration groups showed no significant differences in bleeding severity. However, the PCAB group demonstrated significantly fewer ulcer lesions with recent bleeding stigmata and required fewer therapeutic endoscopic interventions. Additionally, re-bleeding events were more frequent in the PPI group. These findings suggest that pre-endoscopic administration of PCABs may be more effective than PPIs and could potentially reduce mortality associated with ulcer bleeding.
Publish Date 2025-06-11 06:21
Citation <p>Lim NR, Chung WC. Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers. <i>World J Gastrointest Endosc</i> 2025; 17(6): 104234</p>
URL https://www.wjgnet.com/1948-5190/full/v17/i6/104234.htm
DOI https://dx.doi.org/10.4253/wjge.v17.i6.104234
Full Article (PDF) WJGE-17-104234-with-cover.pdf
Manuscript File 104234_Auto_Edited_070108.docx
Answering Reviewers 104234-answering-reviewers.pdf
Audio Core Tip 104234-audio.m4a
Biostatistics Review Certificate 104234-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 104234-conflict-of-interest-statement.pdf
Copyright License Agreement 104234-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 104234-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 104234-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 104234-non-native-speakers.pdf
Peer-review Report 104234-peer-reviews.pdf
Scientific Misconduct Check 104234-scientific-misconduct-check.png
Scientific Editor Work List 104234-scientific-editor-work-list.pdf
CrossCheck Report 104234-crosscheck-report.pdf