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Articles Published Processes
6/11/2025 6:21:38 AM | Browse: 7 | Download: 0
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Received |
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2024-12-16 08:18 |
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Peer-Review Started |
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2024-12-16 08:19 |
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To Make the First Decision |
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Return for Revision |
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2025-03-01 06:33 |
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Revised |
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2025-03-29 05:00 |
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Second Decision |
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2025-05-13 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-13 08:54 |
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Articles in Press |
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2025-05-13 08:54 |
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Publication Fee Transferred |
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2025-04-03 02:32 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-04 01:41 |
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Publish the Manuscript Online |
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2025-06-11 06:21 |
ISSN |
1948-5190 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Na Rae Lim and Woo Chul Chung |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Woo Chul Chung, MD, PhD, Professor, Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University, Jungbu-daero 93, Seoul 16247, South Korea. jwchulkr@catholic.ac.kr |
Key Words |
Peptic ulcer; Bleeding; Proton pump inhibitor; Potassium competitive acid blocker; Ulcer bleeding |
Core Tip |
This study compared the effectiveness of intravenous proton pump inhibitors (PPIs) and oral potassium competitive acid blockers (PCABs) in managing non-variceal upper gastrointestinal bleeding prior to emergency endoscopy. PPI injection and PCAB administration groups showed no significant differences in bleeding severity. However, the PCAB group demonstrated significantly fewer ulcer lesions with recent bleeding stigmata and required fewer therapeutic endoscopic interventions. Additionally, re-bleeding events were more frequent in the PPI group. These findings suggest that pre-endoscopic administration of PCABs may be more effective than PPIs and could potentially reduce mortality associated with ulcer bleeding. |
Publish Date |
2025-06-11 06:21 |
Citation |
<p>Lim NR, Chung WC. Intravenous proton pump inhibitors vs oral potassium competitive acid blockers before endoscopic treatment of bleeding peptic ulcers. <i>World J Gastrointest Endosc</i> 2025; 17(6): 104234</p> |
URL |
https://www.wjgnet.com/1948-5190/full/v17/i6/104234.htm |
DOI |
https://dx.doi.org/10.4253/wjge.v17.i6.104234 |
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