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Articles Published Processes
6/20/2025 8:05:13 AM | Browse: 20 | Download: 141
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Received |
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2024-12-16 07:06 |
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Peer-Review Started |
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2024-12-16 07:06 |
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To Make the First Decision |
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Return for Revision |
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2025-03-11 08:45 |
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Revised |
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2025-03-20 06:43 |
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Second Decision |
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2025-05-06 02:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-07 09:40 |
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Articles in Press |
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2025-05-07 09:40 |
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Publication Fee Transferred |
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2025-04-09 04:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-09 01:03 |
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Publish the Manuscript Online |
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2025-06-20 08:05 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Retrospective Study |
Article Title |
Phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high colorectal carcinomas
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Anurag Mehta, Divya Bansal, Rupal Tripathi and Vidya Anoop |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Divya Bansal, MD, Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector 5, New Delhi 110085, Delhi, India. divyabansalrgci@gmail.com |
Key Words |
Mismatch repair; Microsatellite instability; Lymph node yield; Lymph node ratio; Colorectal carcinoma |
Core Tip |
Mismatch repair deficient/microsatellite instability-high (MMR-D/MSI-H) colorectal cancers (CRCs) account for 15% of CRCs exhibiting peculiar clinicopathological features. The correlation between MMR-D/MSI-H status and distinct lymph node characteristics, including increased lymph node yield, low lymph node ratio, and larger uninvolved node size, suggests a potential link to the heightened immune response typical of these cancers. These findings reinforce the promising prognosis associated with MMR-D/MSI-H CRC, reflecting improved overall survival rates compared to mismatch repair proficient or microsatellite stable tumors and offering valuable insights for tailored therapeutic approaches in this specific subtype of CRC. |
Publish Date |
2025-06-20 08:05 |
Citation |
<p>Mehta A, Bansal D, Tripathi R, Anoop V. Phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high colorectal carcinomas. <i>World J Clin Oncol</i> 2025; 16(6): 104243</p> |
URL |
https://www.wjgnet.com/2218-4333/full/v16/i6/104243.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v16.i6.104243 |
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