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Articles Published Processes
5/26/2025 7:26:12 AM | Browse: 132 | Download: 840
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Received |
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2024-12-16 03:53 |
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Peer-Review Started |
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2024-12-16 03:53 |
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First Decision by Editorial Office Director |
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2025-03-05 01:31 |
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Return for Revision |
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2025-03-05 04:29 |
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Revised |
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2025-03-16 13:46 |
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Publication Fee Transferred |
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2025-03-18 15:47 |
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Second Decision by Editor |
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2025-04-10 03:10 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-11 02:19 |
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Articles in Press |
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2025-04-11 02:19 |
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Edit the Manuscript by Language Editor |
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2025-04-18 00:30 |
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Typeset the Manuscript |
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2025-05-21 00:53 |
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Publish the Manuscript Online |
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2025-05-26 07:26 |
| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Diagnostic accuracy of noninvasive steatosis biomarkers with magnetic resonance imaging proton density fat fraction as gold standard
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Liang Chen, Shao-Jie Duan, Sheng Xie and Shu-Kun Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Leap-forward Development Program for Beijing Biopharmaceutical Industry (G20) |
Z171100001717008 |
| the Fundamental Research Funds for the Central Universities and Research projects on biomedical transformation of China-Japan Friendship Hospital |
PYBZ1815 |
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| Corresponding Author |
Shu-Kun Yao, Chief Physician, MD, Professor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, China., Beijing 100029, China. yao_sk@126.com |
| Key Words |
Nonalcoholic fatty liver disease; Diagnosis; Noninvasive biomarker; Magnetic resonance imaging proton density fat fraction; Chinese population |
| Core Tip |
This is the first study to investigate the accuracy of noninvasive biomarkers for detecting nonalcoholic fatty liver disease (NAFLD) based on magnetic resonance imaging proton density fat fraction (MRI-PDFF) in the Chinese population, which is currently considered a novel gold standard for hepatic steatosis. Two types of cut-offs (single optimal cut-off and dual cut-off) of six steatosis biomarkers were analyzed. These noninvasive steatosis biomarkers demonstrated great accuracy in diagnosing NAFLD (MRI-PDFF ≥ 5%) and exhibited a strong correlation with MRI-PDFF. However, they may be ineffective in the detection of moderate or severe steatosis. |
| Publish Date |
2025-05-26 07:26 |
| Citation |
Chen JL, Duan SJ, Xie S, Yao SK. Diagnostic accuracy of noninvasive steatosis biomarkers with magnetic resonance imaging proton density fat fraction as gold standard. World J Radiol 2025; 17(5): 104272 |
| URL |
https://www.wjgnet.com/1949-8470/full/v17/i5/104272.htm |
| DOI |
https://dx.doi.org/10.4329/wjr.v17.i5.104272 |
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