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Articles Published Processes
4/18/2025 8:22:14 AM | Browse: 43 | Download: 176
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Received |
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2024-12-18 09:23 |
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Peer-Review Started |
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2024-12-18 09:23 |
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First Decision by Editorial Office Director |
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2025-02-18 10:10 |
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Return for Revision |
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2025-02-18 10:10 |
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Revised |
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2025-03-02 08:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-03-10 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-03-10 08:02 |
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Articles in Press |
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2025-03-10 08:02 |
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Edit the Manuscript by Language Editor |
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2025-03-17 01:40 |
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Typeset the Manuscript |
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2025-03-30 14:01 |
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Publish the Manuscript Online |
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2025-04-18 08:22 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Impact of low-level pre-transplant donor-specific antibodies detected by Luminex platform on acute rejection and long-term graft survival
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Khawar Abbas, Muhammed Mubarak, Wajiha Musharraf, Abdul Rauf Hafeez, Tahir Aziz and Mirza Naqi Zafar |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Khawar Abbas, Professor, Department of Transplant Immunology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sind, Pakistan. drkhawar_imuno@yahoo.com |
| Key Words |
Pre-transplant; DSA; Luminex; Kidney transplant; Rejection; Graft outcomes |
| Core Tip |
Pre-transplant low-level donor-specific antibodies (DSAs) detected by the Luminex platform alone, are associated with favorable graft outcomes at one and 10 years in kidney transplant recipients. This study highlights that with appropriate immunosuppressive induction and maintenance protocols, these patients experience low rates of acute rejection (AR) and sustain satisfactory long-term graft function and survival. The majority of patients who experienced AR showed a resolution of DSAs, underscoring the dynamic nature of antibodies. These findings support the clinical relevance of Luminex-detected low-level DSAs and reinforce the efficacy of contemporary immunosuppressive strategies in optimizing graft survival in this subset of transplant recipients. |
| Publish Date |
2025-04-18 08:22 |
| Citation |
Abbas K, Mubarak M, Musharraf W, Hafeez AR, Aziz T, Zafar MN. Impact of low-level pre-transplant donor-specific antibodies detected by Luminex platform on acute rejection and long-term graft survival. World J Transplant 2025; 15(3): 104308 |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i3/104308.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i3.104308 |
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