Publication Name	World Journal of Clinical Oncology
Manuscript ID	104314
Country	Greece

Received	2024-12-20 10:40
Peer-Review Started	2024-12-20 10:40
To Make the First Decision
Return for Revision	2025-02-10 09:09
Revised	2025-02-10 22:54
Second Decision	2025-03-05 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-05 12:16
Articles in Press	2025-03-05 12:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-14 01:51
Publish the Manuscript Online	2025-06-20 08:05

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Editorial
Article Title	Immunotherapy in gastrointestinal stromal tumors: Current landscape and future horizons
Manuscript Source	Invited Manuscript
All Author List	Stavros P Papadakos, Alexandra Argyrou, Ioannis Karniadakis, Stamatina Vogli and Stamatios Theocharis
ORCID	Author(s) ORCID Number Stavros P Papadakos http://orcid.org/0000-0003-1583-1125 Alexandra Argyrou http://orcid.org/0000-0002-1569-5592 Ioannis Karniadakis http://orcid.org/0000-0001-9924-0044 Stamatina Vogli http://orcid.org/0000-0003-4944-2611 Stamatios Theocharis http://orcid.org/0000-0002-0930-1657
Funding Agency and Grant Number
Corresponding Author
Key Words	Immunotherapy strategies; Biomarker-driven therapy; Immune checkpoint inhibitors; Tumor microenvironment; Gastrointestinal stromal tumors
Core Tip	Immunotherapy for gastrointestinal stromal tumors (GISTs) remains an emerging field with promising but early-stage developments. This editorial summarizes the current landscape of immunotherapy in GISTs, focusing on the immune microenvironment, advances in biomarker discovery, and innovative strategies such as immune checkpoint inhibitors, cytokine-based therapies, and adoptive cell therapies. Future directions emphasize the integration of immune profiling and personalized combination therapies to optimize treatment outcomes. Understanding these dynamics will be essential for overcoming resistance and improving precision oncology in GIST management.
Publish Date	2025-06-20 08:05
Citation	<p>Papadakos SP, Argyrou A, Karniadakis I, Vogli S, Theocharis S. Immunotherapy in gastrointestinal stromal tumors: Current landscape and future horizons. <i>World J Clin Oncol</i> 2025; 16(6): 104314</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i6/104314.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i6.104314

Full Article (PDF)	WJCO-16-104314-with-cover.pdf
Manuscript File	104314_Auto_Edited_115523.docx
Answering Reviewers	104314-answering-reviewers.pdf
Audio Core Tip	104314-audio.m4a
Conflict-of-Interest Disclosure Form	104314-conflict-of-interest-statement.pdf
Copyright License Agreement	104314-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	104314-non-native-speakers.pdf
Peer-review Report	104314-peer-reviews.pdf
Scientific Misconduct Check	104314-scientific-misconduct-check.png
Scientific Editor Work List	104314-scientific-editor-work-list.pdf
CrossCheck Report	104314-crosscheck-report.pdf