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Articles Published Processes
11/19/2025 5:57:29 AM | Browse: 72 | Download: 215
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Received |
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2024-12-18 10:20 |
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Peer-Review Started |
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2024-12-18 10:20 |
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First Decision by Editorial Office Director |
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2025-03-10 03:25 |
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Return for Revision |
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2025-03-10 03:25 |
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Revised |
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2025-03-20 02:14 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-04-08 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-08 11:17 |
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Articles in Press |
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2025-04-08 11:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-30 12:45 |
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Publish the Manuscript Online |
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2025-11-19 05:57 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Utility and limitations of the use of donor-derived cell-free DNA in kidney transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maurizio Salvadori and Giuseppina Rosso |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Tuscany, Italy. maurizio.salvadori1@gmail.com |
| Key Words |
Biomarkers; Donor-derived cell-free DNA; Antibody mediated rejection; T cell mediated rejection; Subclinical rejection; Advantages and disadvantages |
| Core Tip |
New biomarkers have allowed to improving our knowledge in clinical medicine, in the field of transplantation in particular. Donor-derived cell-free DNA has proven to be one of the best. Such donor DNA is delivered from the damaged graft into the bloodstream of the recipient. The finding of donor-derived cell-free DNA is a clear sign of damaged graft, more often involving the endothelial cells. Several pathologies may be the cause, most often antibody-mediated rejection. Less frequent, T-cell mediated rejection. Major advantage of such technique is to avoid invasive procedures as renal biopsy. |
| Publish Date |
2025-11-19 05:57 |
| Citation |
Salvadori M, Rosso G. Utility and limitations of the use of donor-derived cell-free DNA in kidney transplantation. World J Transplant 2025; 15(4): 104349 |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i4/104349.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i4.104349 |
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