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Articles Published Processes
4/25/2025 7:53:58 AM | Browse: 2 | Download: 0
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Received |
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2024-12-18 11:45 |
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Peer-Review Started |
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2024-12-20 00:27 |
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To Make the First Decision |
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Return for Revision |
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2025-01-20 08:15 |
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Revised |
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2025-01-27 12:37 |
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Second Decision |
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2025-02-20 02:49 |
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Accepted by Journal Editor-in-Chief |
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2025-02-23 21:30 |
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Accepted by Executive Editor-in-Chief |
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2025-03-03 06:59 |
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Articles in Press |
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2025-03-03 06:59 |
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Publication Fee Transferred |
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2025-01-29 13:27 |
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Edit the Manuscript by Language Editor |
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2025-03-10 01:17 |
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Typeset the Manuscript |
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2025-03-13 00:41 |
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Publish the Manuscript Online |
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2025-04-25 07:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Role of nuclear factor erythroid 2-related factor 2 in negative pressure wound therapy for diabetic foot ulcers
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao-Jie Sun, Shan-Wen Si, Ya-Mei Ma, Xue-Kui Liu, Hou-Fa Geng and Jun Liang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jun Liang, PhD, Professor, Department of Endocrinology, Xuzhou Central Hospital, No. 199 Jiefang South Road, Xuzhou 221009, Jiangsu Province, China. mwlj521@njmu.edu.cn |
| Key Words |
Negative pressure wound therapy; Diabetic foot ulcers; Nuclear factor erythroid 2-related factor 2; Kelch-like epichlorohydrin-associated protein 1; Healing |
| Core Tip |
This study investigates the role of negative pressure wound therapy (NPWT) in diabetic foot ulcers (DFUs) by assessing wound healing, inflammatory markers, cytokines, growth factors, and oxidative stress. NPWT significantly improved wound conditions and reduced inflammation while increasing angiogenesis markers and antioxidant defenses mediated by nuclear factor erythroid 2-related factor 2 (Nrf2). The study suggests that Nrf2 activation is a key mechanism in the therapeutic effects of NPWT on DFUs. |
| Publish Date |
2025-04-25 07:53 |
| Citation |
<p>Sun HJ, Si SW, Ma YM, Liu XK, Geng HF, Liang J. Role of nuclear factor erythroid 2-related factor 2 in negative pressure wound therapy for diabetic foot ulcers. <i>World J Diabetes</i> 2025; 16(5): 104350</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i5/104350.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i5.104350 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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