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Articles Published Processes
3/12/2025 5:57:36 AM | Browse: 31 | Download: 45
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Received |
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2024-12-23 13:04 |
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Peer-Review Started |
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2024-12-23 13:04 |
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To Make the First Decision |
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Return for Revision |
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2025-01-24 07:16 |
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Revised |
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2025-02-06 10:25 |
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Second Decision |
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2025-02-27 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-27 10:56 |
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Articles in Press |
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2025-02-27 10:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-05 03:37 |
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Publish the Manuscript Online |
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2025-03-12 05:57 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Requirements for standardizing the assessment of mesenchymal stem cell therapy and its effects on osteoarthritis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yu-Chen Wang, Jing-Bo Cheng and Ming-Li Feng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Capital Fund Project for Clinical Diagnosis and Treatment Technology Research and Translational Application |
Z201100005520091 |
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| Corresponding Author |
Ming-Li Feng, Chief Physician, MD, Department of Orthopaedic Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Ave, Xicheng District, Beijing 100053, China. fengmingli6666@163.com |
| Key Words |
Osteoarthritis; Mesenchymal stem cell therapy; Assessment; Heterogeneity; Safety |
| Core Tip |
Intra-articular injection of mesenchymal stem cell (MSC) has emerged as a promising strategy for osteoarthritis treatment due to its potential to promote cartilage regeneration, modulate inflammation, and improve joint function. Despite encouraging preliminary results, the clinical translation of this therapy is hindered by the absence of standardized evaluation criteria. Key challenges include inconsistent methods for assessing treatment efficacy, cell source heterogeneity, and concerns about tumorigenicity and biodistribution. Therefore, we proposed a set of factors and efficacy evaluation standards that should be considered in preclinical studies and MSC therapy. |
| Publish Date |
2025-03-12 05:57 |
| Citation |
<p>Wang YC, Cheng JB, Feng ML. Requirements for standardizing the assessment of mesenchymal stem cell therapy and its effects on osteoarthritis. <i>World J Orthop</i> 2025; 16(3): 104451</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i3/104451.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i3.104451 |
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