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Articles Published Processes
4/25/2025 7:53:51 AM | Browse: 93 | Download: 637
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Received |
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2024-12-24 05:41 |
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Peer-Review Started |
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2024-12-24 09:21 |
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First Decision by Editorial Office Director |
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2025-01-15 10:23 |
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Return for Revision |
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2025-01-15 10:23 |
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Revised |
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2025-02-05 15:38 |
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Publication Fee Transferred |
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2025-02-10 09:32 |
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Second Decision by Editor |
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2025-02-19 12:54 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-02-26 07:56 |
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Articles in Press |
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2025-02-26 07:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-10 00:50 |
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Publish the Manuscript Online |
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2025-04-25 07:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Systemic immune indicators for predicting renal damage in newly diagnosed type 1 diabetic children
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lan-Fang Cao, Qing-Bo Xu and Li Yang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangxi Provincial Health Commission Science and Technology Plan |
SKJP220212334 |
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| Corresponding Author |
Li Yang, Chief Physician, Professor, Department of Endocrinology, Jiangxi Provincial Children’s Hospital/The Affiliated Children’s Hospital of Nanchang Medical College, No. 1666 Diezihu Avenue, Honggutan District, Nanchang 330038, Jiangxi Province, China. yangli1@ncmc.edu.cn |
| Key Words |
Pediatric type 1 diabetes mellitus; Systemic immune inflammation index; Kidney injury; Urinary albumin-to-creatinine ratio; Inflammatory markers |
| Core Tip |
This study highlights the predictive value of systemic inflammatory markers - systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio - for early kidney damage in children with newly diagnosed type 1 diabetes mellitus. SII emerged as a significant independent predictor of renal injury, with a high specificity threshold. The combination of SII with neutrophil-to-lymphocyte ratio or platelet-to-lymphocyte ratio further enhanced diagnostic accuracy. These simple, cost-effective markers provide valuable tools for early detection and intervention, paving the way for improved clinical strategies to prevent diabetic nephropathy in pediatric type 1 diabetes mellitus patients. |
| Publish Date |
2025-04-25 07:53 |
| Citation |
Cao LF, Xu QB, Yang L. Systemic immune indicators for predicting renal damage in newly diagnosed type 1 diabetic children. World J Diabetes 2025; 16(5): 104482 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i5/104482.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i5.104482 |
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