Publication Name	World Journal of Transplantation
Manuscript ID	104500
Country	India

Received	2024-12-23 04:55
Peer-Review Started	2024-12-23 04:56
To Make the First Decision
Return for Revision	2025-02-24 03:51
Revised	2025-03-09 19:31
Second Decision	2025-03-19 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-21 02:13
Articles in Press	2025-03-21 02:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-07 03:18
Publish the Manuscript Online	2025-04-18 08:22

ISSN	2220-3230 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Editorial
Article Title	Frailty as a determinant of liver transplant outcomes: A call for integrative strategies
Manuscript Source	Invited Manuscript
All Author List	Hirak Pahari, Shikhar Tripathi and Samiran Nundy
ORCID	Author(s) ORCID Number Hirak Pahari http://orcid.org/0000-0002-1946-680X Shikhar Tripathi http://orcid.org/0000-0002-2148-9058 Samiran Nundy http://orcid.org/0000-0002-1757-3919
Funding Agency and Grant Number
Corresponding Author	Hirak Pahari, MD, Department of Liver Transplant and Hepatobiliary Surgery, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi 110060, Delhi, India. hirak.pahari@gmail.com
Key Words	Frailty; Liver transplant; Outcomes; Sarcopenia; Index; Hand grip; Score; Strategies
Core Tip	Frailty has emerged as a pivotal determinant of post-liver transplant (LT) outcomes, yet its integration into clinical practice remains inconsistent. Recent findings suggest that frail recipients experience significantly higher mortality within the first 12 months following transplantation—a period when traditional monitoring often wanes. Frailty, as a dynamic and modifiable condition, represents an opportunity for targeted intervention. Prehabilitation programs focusing on nutritional optimization, physical rehabilitation, and psychosocial support could enhance resilience in transplant candidates, reducing their risk profile and improving post-transplant outcomes. By addressing frailty comprehensively, we can move toward more personalized, effective strategies that improve survival and quality of life for LT recipients.
Publish Date	2025-04-18 08:22
Citation	<p>Pahari H, Tripathi S, Nundy S. Frailty as a determinant of liver transplant outcomes: A call for integrative strategies. <i>World J Transplant</i> 2025; 15(3): 104500</p>
URL	https://www.wjgnet.com/2220-3230/full/v15/i3/104500.htm
DOI	https://dx.doi.org/10.5500/wjt.v15.i3.104500

Full Article (PDF)	WJT-15-104500-with-cover.pdf
Manuscript File	104500_Auto_Edited_084359.docx
Answering Reviewers	104500-answering-reviewers.pdf
Audio Core Tip	104500-audio.mp4
Conflict-of-Interest Disclosure Form	104500-conflict-of-interest-statement.pdf
Copyright License Agreement	104500-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	104500-non-native-speakers.pdf
Peer-review Report	104500-peer-reviews.pdf
Scientific Misconduct Check	104500-scientific-misconduct-check.png
Scientific Editor Work List	104500-scientific-editor-work-list.pdf
CrossCheck Report	104500-crosscheck-report.pdf