Publication Name	World Journal of Hepatology
Manuscript ID	104533
Country	China

Received	2024-12-25 10:46
Peer-Review Started	2024-12-30 08:22
To Make the First Decision
Return for Revision	2025-03-21 07:58
Revised	2025-04-17 04:18
Second Decision	2025-06-04 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-04 09:30
Articles in Press	2025-06-04 09:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-16 07:24
Publish the Manuscript Online	2025-06-26 07:27

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Minireviews
Article Title	Hepatocyte-intrinsic innate immunity in hepatitis B virus infection: A focused review
Manuscript Source	Invited Manuscript
All Author List	Ping Chen, Jing Zhao, Ning-Kai Chen and Zhi-Ying Chen
ORCID	Author(s) ORCID Number Ping Chen http://orcid.org/0000-0003-0131-6499
Funding Agency and Grant Number	Funding Agency Grant Number Shenzhen Medical Academy of Research and Translation D2301010 Shenzhen Science and Technology Innovation Commission RCYX20231211090346060
Corresponding Author	Ping Chen, PhD, Department of Research and Development, Syno Minicircle Biotechnology Co. Ltd., A1003, Gaoke Innovation Center, Guangqiao Road, Guangming District, Shenzhen 518107, Guangdong Province, China. pingchen09@gmail.com
Key Words	Hepatitis B virus; Innate immunity; Immune evasion; Pathogen recognition receptors; Pathogen-associated molecular patterns
Core Tip	Despite the advancements in hepatitis B virus (HBV) immunology, the mechanism by which hepatocytes exert their innate immune responses against HBV infection remains poorly understood. This article focused on the complex interplay between hepatocytes and the innate immune response during HBV infection and summarized the recent findings about how HBV evading the innate response to promoter viral persistence. These insights may be helpful for developing novel anti-HBV immune-based therapies.
Publish Date	2025-06-26 07:27
Citation	<p>Chen P, Zhao J, Chen NK, Chen ZY. Hepatocyte-intrinsic innate immunity in hepatitis B virus infection: A focused review. <i>World J Hepatol</i> 2025; 17(6): 104533</p>
URL	https://www.wjgnet.com/1948-5182/full/v17/i6/104533.htm
DOI	https://dx.doi.org/10.4254/wjh.v17.i6.104533

Full Article (PDF)	WJH-17-104533-with-cover.pdf
Manuscript File	104533_Auto_Edited_055757.docx
Answering Reviewers	104533-answering-reviewers.pdf
Audio Core Tip	104533-audio.mp3
Conflict-of-Interest Disclosure Form	104533-conflict-of-interest-statement.pdf
Copyright License Agreement	104533-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	104533-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	104533-non-native-speakers.pdf
Peer-review Report	104533-peer-reviews.pdf
Scientific Misconduct Check	104533-scientific-misconduct-check.png
Scientific Editor Work List	104533-scientific-editor-work-list.pdf
CrossCheck Report	104533-crosscheck-report.pdf