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6/11/2025 6:21:38 AM | Browse: 11 | Download: 130
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 104539
Country Pakistan
Received
2024-12-25 11:23
Peer-Review Started
2024-12-25 11:23
To Make the First Decision
Return for Revision
2025-03-06 19:01
Revised
2025-03-18 16:46
Second Decision
2025-05-06 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-07 09:48
Articles in Press
2025-05-07 09:48
Publication Fee Transferred
2025-04-03 09:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-30 08:29
Publish the Manuscript Online
2025-06-11 06:21
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Diagnostic role of endoscopic ultrasonography in defining the clinical features and histopathological spectrum of gastroenteropancreatic neuroendocrine tumors
Manuscript Source Unsolicited Manuscript
All Author List Syedda Ayesha, Masood Muhammad Karim, Abdul Hadi Shahid, Adeel Ur Rehman, Zeeshan Uddin and Shahab Abid
ORCID
Author(s) ORCID Number
Syedda Ayesha http://orcid.org/0009-0007-4893-3335
Masood Muhammad Karim http://orcid.org/0000-0002-2513-7842
Abdul Hadi Shahid http://orcid.org/0009-0007-2392-3376
Shahab Abid http://orcid.org/0000-0003-2520-0378
Funding Agency and Grant Number
Corresponding Author Shahab Abid, Professor, Section of Gastroenterology, Department of Medicine, Aga Khan University, Stadium Road, P O Box 3500, Karachi 74800, Sindh, Pakistan. shahab.abid@aku.edu
Key Words Developing countries; Immunohistochemistry; Endoscopic ultrasound-guided fine needle aspiration; Fine-needle; Biopsy; Neoplasm grading; Endosonography; Diagnostic imaging; Gastro-enteropancreatic neuroendocrine tumors; Neuroendocrine tumors
Core Tip Despite its proven diagnostic utility, data on endoscopic ultrasonography (EUS) in resource-constrained settings remains limited. This study evaluates the role of EUS in diagnosing gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) at a tertiary hospital in Pakistan. Among 14 patients, EUS-guided fine-needle biopsy achieved a 100% diagnostic yield, with the pancreas as the most common tumor site (57.1%). Histopathology revealed 78.6% as well-differentiated NETs, and metastases were observed in 57.1% of cases, primarily to the liver. EUS proved invaluable in detecting small lesions, assessing tumor depth, and guiding management, reinforcing its role as the gold standard for GEP-NET diagnosis in low-resource settings.
Publish Date 2025-06-11 06:21
Citation <p>Ayesha S, Karim MM, Shahid AH, Rehman AU, Uddin Z, Abid S. Diagnostic role of endoscopic ultrasonography in defining the clinical features and histopathological spectrum of gastroenteropancreatic neuroendocrine tumors. <i>World J Gastrointest Endosc</i> 2025; 17(6): 104539</p>
URL https://www.wjgnet.com/1948-5190/full/v17/i6/104539.htm
DOI https://dx.doi.org/10.4253/wjge.v17.i6.104539
Full Article (PDF) WJGE-17-104539-with-cover.pdf
Manuscript File 104539_Auto_Edited_060027.docx
Answering Reviewers 104539-answering-reviewers.pdf
Audio Core Tip 104539-audio.m4a
Biostatistics Review Certificate 104539-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 104539-conflict-of-interest-statement.pdf
Copyright License Agreement 104539-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 104539-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 104539-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 104539-non-native-speakers.pdf
Peer-review Report 104539-peer-reviews.pdf
Scientific Misconduct Check 104539-scientific-misconduct-check.png
Scientific Editor Work List 104539-scientific-editor-work-list.pdf
CrossCheck Report 104539-crosscheck-report.pdf