| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Risks of liver cirrhosis, hepatocellular carcinoma, hepatic-related complications, and mortality in patients with type 2 diabetes in Taiwan
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua-Fen Chen, Yung-Yueh Chang, Peter Chen, Xiao-Han Shen, Chin-Huan Chang and Wan-Lun Hsu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Far Eastern Memorial Hospital |
FEMH-2023-C-082 |
| Far Eastern Memorial Hospital |
FEMH-2022-C-015 |
| Far Eastern Memorial Hospital |
FEMH-2022-C-017 |
|
| Corresponding Author |
Hua-Fen Chen, Assistant Professor, Chief, MD, Department of Endocrinology, Far Eastern Memorial Hospital, No. 21 Section 2, Nanya S Road, Banqiao District, New Taipei City 220, Taiwan. hfchen@mail.femh.org.tw |
| Key Words |
Type 2 diabetes mellitus; Liver cirrhosis; Hepatocellular carcinoma; Hepatic-related complications; Mortality; Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis |
| Core Tip |
Nonalcoholic, hepatitis B and C serologically negative patients with type 2 diabetes, one of the cardiometabolic risk factors for metabolic dysfunction-associated steatotic liver disease, exhibited independently increased risks of cirrhosis of the liver, hepatocellular carcinoma, hepatic-related complications, and mortality, irrespective of age or sex. Coexisting obesity, hypertension, and dyslipidemia worsened this risk, but regular exercise could ameliorate hepatic outcomes even after adjustment for confounders. |
| Publish Date |
2025-04-25 07:54 |
| Citation |
<p>Chen HF, Chang YY, Chen P, Shen XH, Chang CH, Hsu WL. Risks of liver cirrhosis, hepatocellular carcinoma, hepatic-related complications, and mortality in patients with type 2 diabetes in Taiwan. <i>World J Diabetes</i> 2025; 16(5): 104576</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i5/104576.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i5.104576 |
