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4/25/2025 8:22:59 AM | Browse: 9 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 104622
Country China
Received
2024-12-26 06:28
Peer-Review Started
2024-12-30 01:28
To Make the First Decision
Return for Revision
2025-02-26 08:56
Revised
2025-02-26 15:01
Second Decision
2025-03-06 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-06 10:26
Articles in Press
2025-03-06 10:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-01 01:30
Publish the Manuscript Online
2025-04-25 08:22
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Combining nutraceuticals and a mediterranean diet for managing metabolic dysfunction associated with steatotic liver disease
Manuscript Source Invited Manuscript
All Author List Fei-Yong Cheng, Cong Chen, Feng-Yong Wang and Bo-Huan Zhao
ORCID
Author(s) ORCID Number
Fei-Yong Cheng http://orcid.org/0009-0008-3575-6568
Cong Chen http://orcid.org/0009-0004-4431-0702
Feng-Yong Wang http://orcid.org/0009-0004-4168-9219
Bo-Huan Zhao http://orcid.org/0009-0003-7314-0071
Funding Agency and Grant Number
Corresponding Author Bo-Huan Zhao, Chief Physician, Postdoctoral Fellow, Senior Researcher, Department of General Surgery, Zhuji Traditional Chinese Medicine Hospital, No. 521 Donger Road, Huandong Street, Zhuji 311899, Zhejiang Province, China. 448322750@qq.com
Key Words Alpha-lipoic acid; Dietary interventions; Metabolic dysfunction-associated steatotic liver disease; Silybum marianum; Synergistic effects; Vitamin E
Core Tip This study demonstrated the therapeutic potential of combining α-lipoic acid and Silybum marianum supplementation with a Mediterranean diet for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). While the intervention reduced visceral adiposity and improved hepatic steatosis markers, key metabolic parameters, including transaminase levels and lipid profiles, remained unchanged. Future investigations should prioritize (1) Mechanistic studies on antioxidant and anti-inflammatory pathways; (2) Exploration of synergistic combinations with complementary nutraceuticals; and (3) Extended follow-up periods to evaluate long-term efficacy and safety. Importantly, patient stratification accounting for disease severity and comorbidity profiles will be essential for developing personalized treatment strategies in MASLD management.
Publish Date 2025-04-25 08:22
Citation <p>Cheng FY, Chen C, Wang FY, Zhao BH. Combining nutraceuticals and a mediterranean diet for managing metabolic dysfunction associated with steatotic liver disease. <i>World J Hepatol</i> 2025; 17(4): 104622</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i4/104622.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i4.104622
Full Article (PDF) WJH-17-104622-with-cover.pdf
Manuscript File 104622_Auto_Edited_035300.docx
Answering Reviewers 104622-answering-reviewers.pdf
Audio Core Tip 104622-audio.m4a
Conflict-of-Interest Disclosure Form 104622-conflict-of-interest-statement.pdf
Copyright License Agreement 104622-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 104622-non-native-speakers.pdf
Peer-review Report 104622-peer-reviews.pdf
Scientific Misconduct Check 104622-scientific-misconduct-check.png
Scientific Editor Work List 104622-scientific-editor-work-list.pdf
CrossCheck Report 104622-crosscheck-report.pdf