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Articles Published Processes
5/15/2025 10:28:53 AM | Browse: 19 | Download: 42
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Received |
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2025-01-02 11:30 |
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Peer-Review Started |
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2025-01-02 11:30 |
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To Make the First Decision |
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Return for Revision |
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2025-02-13 08:06 |
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Revised |
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2025-02-25 11:31 |
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Second Decision |
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2025-03-13 02:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-13 06:06 |
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Articles in Press |
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2025-03-13 06:06 |
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Publication Fee Transferred |
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2025-02-26 08:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-27 09:26 |
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Publish the Manuscript Online |
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2025-05-15 10:28 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Basic Study |
| Article Title |
Circulating exosomal miR-17-92 cluster serves as a novel noninvasive diagnostic marker for patients with gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ye Han, Xing-Po Guo, Qiao-Ming Zhi, Jing-Jing Xu, Fei Liu and Yu-Ting Kuang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81902805 |
| Jiangsu Provincial Natural Science Foundation |
BK20190174 |
| Suzhou Gusu Health Talent Research Project |
GSWS2023039 |
| Suzhou Medical Youth Talents Project |
Qngg2024004 |
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| Corresponding Author |
Yu-Ting Kuang, MD, Department of General Surgery, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215006, Jiangsu Province, China. sudaytkuang@163.com |
| Key Words |
Gastric cancer; Serum; Exosome; miR-17-92 cluster; Diagnosis |
| Core Tip |
The expression levels of exosomal miR-17-92 clusters were significantly upregulated in the serum of patients with gastric cancer (GC). Elevated expression levels of exosomal miR-17-92 were closely correlated with tumor size, tumor depth, lymph node metastasis, distant metastasis, and tumor-node-metastasis stage of these patients. The combined panel of miR-17, miR-18, miR-19a, and miR-92 showed substantially higher clinical diagnostic value for GC than any individual component or pair. The newly developed panel comprising carcinoembryonic antigen, carbohydrate antigen 19-9, and the four miR-17-92 cluster members exhibited the most robust clinical diagnostic value for GC. |
| Publish Date |
2025-05-15 10:28 |
| Citation |
<p>Han Y, Guo XP, Zhi QM, Xu JJ, Liu F, Kuang YT. Circulating exosomal miR-17-92 cluster serves as a novel noninvasive diagnostic marker for patients with gastric cancer. <i>World J Gastrointest Oncol</i> 2025; 17(5): 104776</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i5/104776.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i5.104776 |
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