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Articles Published Processes
3/18/2025 7:12:51 AM | Browse: 34 | Download: 50
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Received |
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2025-01-02 09:02 |
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Peer-Review Started |
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2025-01-02 09:02 |
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2025-02-18 07:30 |
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2025-02-19 09:05 |
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Second Decision |
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2025-02-26 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-27 11:08 |
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Articles in Press |
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2025-02-27 11:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-07 07:51 |
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Publish the Manuscript Online |
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2025-03-18 07:12 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Human milk oligosaccharide secretion dynamics during breastfeeding and its antimicrobial role: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mohammed Al-Beltagi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed Al-Beltagi, Chief Physician, MD, PhD, Professor, Department of Paediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Alghrabia, Egypt. mbelrem@hotmail.com |
| Key Words |
Human milk oligosaccharides; Human milk oligosaccharides secretion dynamics; Antimicrobial activity; Breastfeeding; Synthetic human milk oligosaccharides; Pathogen adhesion inhibition; Infant health |
| Core Tip |
This systematic review highlights human milk oligosaccharides (HMOs)' dynamic secretion patterns and antimicrobial properties (HMOs), emphasizing their crucial role in infant health. HMOs protect against many pathogens by inhibiting adhesion, disrupting biofilms, and impairing bacterial enzymatic activity. Synthetic HMOs, including 2′-fucosyllactose and 3-fucosyllactose, replicate the structure and function of natural HMOs, offering scalable solutions for therapeutic applications. HMOs also synergize with antibiotics, enhancing their efficacy and addressing antimicrobial resistance. These findings underscore HMOs' potential to develop innovative maternal and neonatal care interventions, improving global health outcomes. |
| Publish Date |
2025-03-18 07:12 |
| Citation |
<p>Al-Beltagi M. Human milk oligosaccharide secretion dynamics during breastfeeding and its antimicrobial role: A systematic review. <i>World J Clin Pediatr</i> 2025; 14(2): 104797</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i2/104797.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i2.104797 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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