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Articles Published Processes
6/18/2025 8:20:51 AM | Browse: 0 | Download: 0
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Received |
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2025-01-06 03:55 |
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Peer-Review Started |
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2025-01-06 03:55 |
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To Make the First Decision |
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Return for Revision |
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2025-02-11 09:08 |
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Revised |
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2025-02-24 13:02 |
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Second Decision |
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2025-05-21 02:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-21 13:20 |
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Articles in Press |
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2025-05-21 13:20 |
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Publication Fee Transferred |
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2025-03-15 11:50 |
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Edit the Manuscript by Language Editor |
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2025-05-27 19:33 |
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Typeset the Manuscript |
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2025-06-04 06:33 |
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Publish the Manuscript Online |
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2025-06-18 08:20 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Review |
| Article Title |
Deciphering the etiology of congenital scoliosis: A genetic and epigenetic perspective
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui Zhao, Ji-Rong Zhao, Xu Xue and Dong Ma |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82460940 |
| Major Project of Gansu Province Joint Fund |
23JRRA1519 |
| Key Science and Technology Project of Gansu Province |
21ZD4FA009 |
| Natural Science Foundation of Gansu Province |
24JRRA1040 |
| Gansu Province Famous Traditional Chinese Medicine Inheritance Studio Project |
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| Corresponding Author |
Ji-Rong Zhao, Chief Physician, Professor, Clinical College of Chinese Medicine, Gansu University of Chinese Medicine, No. 35 Dingxi East Road, Chengguan District, Lanzhou 730000, Gansu Province, China. zhaojirong0709@163.com |
| Key Words |
Congenital scoliosis; Genetics; Epigenetics; Genetic variants; Susceptibility factors |
| Core Tip |
Congenital scoliosis (CS) is a common spinal deformity with complex and not fully understood causes. This review highlights recent advancements in genetic and epigenetic research, focusing on the identification of genetic variants, susceptibility factors, and their regulatory mechanisms. By examining genetic markers, chromosomal abnormalities, and epigenetic modifications, we explore how genetic predisposition interacts with environmental influences in the pathogenesis of CS. This integrated analysis aims to enhance understanding of CS etiology, guiding future clinical interventions and the development of personalized therapeutic approaches. |
| Publish Date |
2025-06-18 08:20 |
| Citation |
<p>Zhao R, Zhao JR, Xue X, Ma D. Deciphering the etiology of congenital scoliosis: A genetic and epigenetic perspective. <i>World J Orthop</i> 2025; 16(6): 104853</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i6/104853.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i6.104853 |
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