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Articles Published Processes
8/14/2025 5:49:33 AM | Browse: 211 | Download: 464
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Received |
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2025-01-10 09:02 |
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Peer-Review Started |
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2025-01-10 09:02 |
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First Decision by Editorial Office Director |
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2025-02-13 08:07 |
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Return for Revision |
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2025-02-13 08:07 |
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Revised |
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2025-04-03 14:29 |
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Publication Fee Transferred |
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2025-04-08 01:26 |
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Second Decision by Editor |
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2025-07-02 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-02 08:33 |
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Articles in Press |
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2025-07-02 08:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 02:10 |
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Publish the Manuscript Online |
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2025-08-14 05:49 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Juan Lyu, Lin Zhou, Xu-Mian Jiang and Dan Zheng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xu-Mian Jiang, Chief Physician, Department of Gastrointestinal Surgery, The Central Hospital of Wuhan, Tongji Medical College, No. 26 Shengli Street, Jiang'an District, Wuhan 430024, Hubei Province, China. baxie52244@163.com |
| Key Words |
Gastric cancer; Chemoresistance; Fatty acid oxidation; Mesenchymal stem cells-derived long non-coding RNAs NKILA; miR-485-5p; STAT3 |
| Core Tip |
Mesenchymal stem cells enhance the stemness and chemoresistance of gastric cancer cells by secreting long non-coding RNAs NKILA, which promotes fatty acid oxidation through STAT3 activation. NKILA modulates the miR-485-5p/STAT3 axis, thereby increasing energy metabolism and supporting cancer stem cell properties. Targeting NKILA or the miR-485-5p/STAT3 pathway offers potential therapeutic strategies to overcome chemoresistance in gastric cancer. |
| Publish Date |
2025-08-14 05:49 |
| Citation |
Lyu XJ, Zhou L, Jiang XM, Zheng D. Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3. World J Gastrointest Oncol 2025; 17(8): 105006
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| URL |
https://www.wjgnet.com/1948-5204/full/v17/i8/105006.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i8.105006 |
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