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8/14/2025 5:49:33 AM | Browse: 30 | Download: 13
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 105006
Country China
Received
2025-01-10 09:02
Peer-Review Started
2025-01-10 09:02
To Make the First Decision
Return for Revision
2025-02-13 08:07
Revised
2025-04-03 14:29
Second Decision
2025-07-02 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-02 08:33
Articles in Press
2025-07-02 08:33
Publication Fee Transferred
2025-04-08 01:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-01 02:10
Publish the Manuscript Online
2025-08-14 05:49
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Juan Lyu, Lin Zhou, Xu-Mian Jiang and Dan Zheng
ORCID
Author(s) ORCID Number
Xu-Mian Jiang http://orcid.org/0009-0006-2017-0623
Funding Agency and Grant Number
Corresponding Author Xu-Mian Jiang, Chief Physician, Department of Gastrointestinal Surgery, The Central Hospital of Wuhan, Tongji Medical College, No. 26 Shengli Street, Jiang'an District, Wuhan 430024, Hubei Province, China. baxie52244@163.com
Key Words Gastric cancer; Chemoresistance; Fatty acid oxidation; Mesenchymal stem cells-derived long non-coding RNAs NKILA; miR-485-5p; STAT3
Core Tip Mesenchymal stem cells enhance the stemness and chemoresistance of gastric cancer cells by secreting long non-coding RNAs NKILA, which promotes fatty acid oxidation through STAT3 activation. NKILA modulates the miR-485-5p/STAT3 axis, thereby increasing energy metabolism and supporting cancer stem cell properties. Targeting NKILA or the miR-485-5p/STAT3 pathway offers potential therapeutic strategies to overcome chemoresistance in gastric cancer.
Publish Date 2025-08-14 05:49
Citation <p>Lyu XJ, Zhou L, Jiang XM, Zheng D. Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3. <i>World J Gastrointest Oncol</i> 2025; 17(8): 105006</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i8/105006.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i8.105006
Full Article (PDF) WJGO-17-105006-with-cover.pdf
Manuscript File 105006_Auto_Edited_015753.docx
Answering Reviewers 105006-answering-reviewers.pdf
Audio Core Tip 105006-audio.mp3
Biostatistics Review Certificate 105006-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105006-conflict-of-interest-statement.pdf
Copyright License Agreement 105006-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 105006-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105006-non-native-speakers.pdf
Peer-review Report 105006-peer-reviews.pdf
Scientific Misconduct Check 105006-scientific-misconduct-check.png
Scientific Editor Work List 105006-scientific-editor-work-list.pdf
CrossCheck Report 105006-crosscheck-report.pdf