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Articles Published Processes
8/14/2025 5:49:33 AM | Browse: 30 | Download: 13
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Received |
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2025-01-10 09:02 |
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Peer-Review Started |
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2025-01-10 09:02 |
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To Make the First Decision |
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Return for Revision |
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2025-02-13 08:07 |
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Revised |
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2025-04-03 14:29 |
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Second Decision |
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2025-07-02 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-02 08:33 |
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Articles in Press |
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2025-07-02 08:33 |
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Publication Fee Transferred |
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2025-04-08 01:26 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 02:10 |
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Publish the Manuscript Online |
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2025-08-14 05:49 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xiao-Juan Lyu, Lin Zhou, Xu-Mian Jiang and Dan Zheng |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Xu-Mian Jiang, Chief Physician, Department of Gastrointestinal Surgery, The Central Hospital of Wuhan, Tongji Medical College, No. 26 Shengli Street, Jiang'an District, Wuhan 430024, Hubei Province, China. baxie52244@163.com |
Key Words |
Gastric cancer; Chemoresistance; Fatty acid oxidation; Mesenchymal stem cells-derived long non-coding RNAs NKILA; miR-485-5p; STAT3 |
Core Tip |
Mesenchymal stem cells enhance the stemness and chemoresistance of gastric cancer cells by secreting long non-coding RNAs NKILA, which promotes fatty acid oxidation through STAT3 activation. NKILA modulates the miR-485-5p/STAT3 axis, thereby increasing energy metabolism and supporting cancer stem cell properties. Targeting NKILA or the miR-485-5p/STAT3 pathway offers potential therapeutic strategies to overcome chemoresistance in gastric cancer. |
Publish Date |
2025-08-14 05:49 |
Citation |
<p>Lyu XJ, Zhou L, Jiang XM, Zheng D. Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3. <i>World J Gastrointest Oncol</i> 2025; 17(8): 105006</p> |
URL |
https://www.wjgnet.com/1948-5204/full/v17/i8/105006.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v17.i8.105006 |
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