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Articles Published Processes
6/13/2025 1:39:38 PM | Browse: 108 | Download: 694
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Received |
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2025-02-07 09:51 |
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Peer-Review Started |
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2025-02-07 09:52 |
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First Decision by Editorial Office Director |
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2025-02-19 06:55 |
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Return for Revision |
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2025-02-19 06:55 |
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Revised |
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2025-03-10 13:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-04-24 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-24 07:21 |
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Articles in Press |
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2025-04-24 07:21 |
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Edit the Manuscript by Language Editor |
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2025-05-01 03:53 |
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Typeset the Manuscript |
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2025-05-30 06:06 |
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Publish the Manuscript Online |
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2025-06-13 13:39 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Role and mechanism of sarcosine dehydrogenase in gallbladder cancer progression through chemokine pathways
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhen Gao, Xin Zhang and Hua He |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Qingpu Science and Technology Commission Project |
QKY2022-13 |
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| Corresponding Author |
Hua He, Department of General Surgery, Qingpu Branch of Zhongshan Hospital, Fudan University, No. 1158 Park Road East, Qingpu District, Shanghai 201700, China. hehua-sh@21cn.com |
| Key Words |
Sarcosine dehydrogenase; Chemokines; Gallbladder cancer; Protein kinase B; Extracellular signal-regulated kinase |
| Core Tip |
In this study, we examined the roles of Sarcosine dehydrogenase (SARDH) and C-X-C motif chemokine ligand 1 (CXCL1) in cancer cells and their effects on key signaling pathways. SARDH silencing enhanced cell proliferation, whereas CXCL1 silencing suppressed migration and invasion, triggering protein kinase B and extracellular signal-regulated kinase signaling pathways. These findings highlight SARDH and CXCL1 as critical regulators of tumor cell behavior and offer new insights into developing targeted cancer therapies. |
| Publish Date |
2025-06-13 13:39 |
| Citation |
Gao Z, Zhang X, He H. Role and mechanism of sarcosine dehydrogenase in gallbladder cancer progression through chemokine pathways. World J Gastrointest Oncol 2025; 17(6): 105016 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/105016.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.105016 |
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