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Articles Published Processes
7/23/2025 11:10:48 AM | Browse: 1 | Download: 0
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Received |
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2025-01-10 09:43 |
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Peer-Review Started |
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2025-01-10 09:43 |
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To Make the First Decision |
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Return for Revision |
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2025-03-18 06:01 |
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Revised |
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2025-03-18 10:55 |
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Second Decision |
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2025-05-21 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-21 06:30 |
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Articles in Press |
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2025-05-21 06:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-08 05:57 |
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Publish the Manuscript Online |
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2025-07-23 11:10 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Association between hereditary spherocytosis and gallstone disease: Pathophysiology, diagnosis, and management
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shan Cong, Yu-Ning Wang, Jun-Rong Wang and Rui-Heng Duan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jun-Rong Wang, Professor, Department of Gynaecology and Obstetrics, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun 130022, Jilin Province, China. junrongwang_2019@yeah.net |
| Key Words |
Hereditary spherocytosis; Gallstone disease; Hemolysis; Bilirubin metabolism; Multidisciplinary management |
| Core Tip |
Hereditary spherocytosis (HS) predisposes patients to gallstone disease due to chronic hemolysis and elevated bilirubin levels. This review explores the pathophysiological mechanisms, clinical manifestations, and diagnostic strategies for hereditary spherocytosis-related gallstones. Key insights include the importance of ultrasonography and magnetic resonance cholangiopancreatography for early detection, tailored management strategies such as splenectomy and cholecystectomy, and emerging preventive approaches, including lifestyle modifications, pharmacological therapies, and novel treatments like nanoprodrugs and probiotics. Addressing research gaps in genetic predisposition, microbial influences, and biomarkers will further enhance prevention and treatment, particularly in pediatric populations, emphasizing a multidisciplinary approach for optimized outcomes. |
| Publish Date |
2025-07-23 11:10 |
| Citation |
<p>Cong S, Wang YN, Wang JR, Duan RH. Association between hereditary spherocytosis and gallstone disease: Pathophysiology, diagnosis, and management. <i>World J Gastrointest Surg</i> 2025; 17(7): 105033</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i7/105033.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i7.105033 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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