Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	105062
Country	China

Received	2025-01-11 05:53
Peer-Review Started	2025-01-11 05:53
To Make the First Decision
Return for Revision	2025-03-06 07:19
Revised	2025-03-20 06:13
Second Decision	2025-04-08 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-08 07:33
Articles in Press	2025-04-08 07:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-05-30 06:06
Publish the Manuscript Online	2025-06-13 13:39

ISSN	1948-5204 (online)
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Category	Oncology
Manuscript Type	Editorial
Article Title	Kinesin family member 14 in digestive tract malignancies: Oncogenic mechanisms, clinical implications, and therapeutic prospects
Manuscript Source	Invited Manuscript
All Author List	De-Hui Li, Chang Qiao, Yu-Tong Han and Jian-Li Ge
ORCID	Author(s) ORCID Number De-Hui Li http://orcid.org/0000-0001-7963-9410
Funding Agency and Grant Number	Funding Agency Grant Number 2023 Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine No. ZF2023165 Key Research and Development Projects of Hebei Province No. 18277731D Natural Science Foundation of Hebei Province No. H202423105 Hebei Provincial Administration of Traditional Chinese Medicine, Scientific Research Project No. 2020014
Corresponding Author	De-Hui Li, MD, Oncology Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Hebei Industrial Technology Institute for Traditional Chinese Medicine Preparation, No. 389 Zhongshan East Road, Chang’an District, Shijiazhuang 050000, Hebei Province, China. 258289951@qq.com
Key Words	Kinesin family member 14; Malignant tumors of the digestive tract; Signaling pathway; Biomarkers; Proliferation; Apoptosis; Migration; Invasion; Angiogenesis
Core Tip	Kinesin family member 14 (KIF14) is pivotal in malignant tumors of the digestive tract. As a crucial driver protein, its elevated expression is intricately linked with tumor biology, drug resistance, progression-free survival, and overall survival, highlighting its potential as a biomarker for early diagnosis, disease monitoring, and prognosis evaluation. Furthermore, recent advancements in targeting KIF14 as a therapeutic target and the regulatory effects of traditional Chinese medicine provide promising new pathways for improving treatment outcomes and enhancing patient prognosis in digestive tract malignancies.
Publish Date	2025-06-13 13:39
Citation	<p>Li DH, Qiao C, Han YT, Ge JL. Kinesin family member 14 in digestive tract malignancies: Oncogenic mechanisms, clinical implications, and therapeutic prospects. <i>World J Gastrointest Oncol</i> 2025; 17(6): 105062</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i6/105062.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i6.105062

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Answering Reviewers	105062-answering-reviewers.pdf
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Scientific Editor Work List	105062-scientific-editor-work-list.pdf
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