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4/27/2025 7:06:36 AM | Browse: 2 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 105066
Country China
Received
2025-01-12 09:41
Peer-Review Started
2025-01-12 09:41
To Make the First Decision
Return for Revision
2025-02-19 02:11
Revised
2025-03-05 02:07
Second Decision
2025-03-26 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-26 08:51
Articles in Press
2025-03-26 08:51
Publication Fee Transferred
2025-03-09 13:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-16 10:31
Publish the Manuscript Online
2025-04-27 07:06
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Application of circulating tumor DNA liquid biopsy in nasopharyngeal carcinoma: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Xin-Yao Zhou, Yuan-Jun Jiang, Xiao-Ming Guo, Dong-Hui Han, Yao Liu and Qiao Qiao
ORCID
Author(s) ORCID Number
Qiao Qiao http://orcid.org/0000-0002-6841-3771
Funding Agency and Grant Number
Funding Agency Grant Number
Beijing Bethune Charitable Foundation and Provincial Natural Science Foundation of Liaoning 2022-MS-190
Corresponding Author Qiao Qiao, Associate Professor, Chief Physician, PhD, Department of Radiation Oncology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110000, Liaoning Province, China. braveheart8063@outlook.com
Key Words Nasopharyngeal cancer; Radiation therapy; Circulating tumor DNA; Epstein–Barr virus; Minor residual disease; Guide treatment; Predicting prognosis; Case report
Core Tip The results of circulating tumor DNA (ctDNA)-based minimal residual disease testing have been used as a biomarker for some solid tumors, but their use as a biomarker to guide the treatment and predict the prognosis of nasopharyngeal carcinoma (NPC) has not yet been reported. We report a patient who tested positive for ctDNA and negative for Epstein‒Barr virus DNA. During the follow-up period, ctDNA signals became positive before tumor progression and became negative again at the end of treatment. This study represents a breakthrough in the use of biomarkers to assess the prognosis of NPC.
Publish Date 2025-04-27 07:06
Citation <p>Zhou XY, Jiang YJ, Guo XM, Han DH, Liu Y, Qiao Q. Application of circulating tumor DNA liquid biopsy in nasopharyngeal carcinoma: A case report and review of literature. <i>World J Clin Cases</i> 2025; 13(21): 105066</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i21/105066.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i21.105066
Full Article (PDF) WJCC-13-105066-with-cover.pdf
CARE Checklist–2016 105066-CARE-Checklist-2016.pdf
Manuscript File 105066_Auto_Edited_062915.docx
Answering Reviewers 105066-answering-reviewers.pdf
Audio Core Tip 105066-audio.mp3
Conflict-of-Interest Disclosure Form 105066-conflict-of-interest-statement.pdf
Copyright License Agreement 105066-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 105066-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s) 105066-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 105066-non-native-speakers.pdf
Peer-review Report 105066-peer-reviews.pdf
Scientific Misconduct Check 105066-scientific-misconduct-check.png
Scientific Editor Work List 105066-scientific-editor-work-list.pdf
CrossCheck Report 105066-crosscheck-report.pdf