Publication Name	World Journal of Gastroenterology
Manuscript ID	105089
Country	China

Received	2025-01-11 05:45
Peer-Review Started	2025-01-11 05:45
To Make the First Decision
Return for Revision	2025-03-11 21:25
Revised	2025-04-27 04:29
Second Decision	2025-07-02 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-02 06:33
Articles in Press	2025-07-02 06:33
Publication Fee Transferred	2025-04-29 02:10
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-22 03:37
Publish the Manuscript Online	2025-07-24 07:47

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease
Manuscript Source	Unsolicited Manuscript
All Author List	Lei Ma, Meng-Han Zhang, Yi-Fan Xu, Yan-Xu Hao, Xuan-Xuan Niu, Yan Li and Hui-Chun Xing
ORCID	Author(s) ORCID Number Lei Ma http://orcid.org/0009-0009-1098-3948 Meng-Han Zhang http://orcid.org/0000-0002-2983-2033 Yi-Fan Xu http://orcid.org/0000-0003-2188-0804 Yan-Xu Hao http://orcid.org/0000-0002-3317-2875 Xuan-Xuan Niu http://orcid.org/0000-0002-7418-2076 Yan Li http://orcid.org/0009-0003-9313-4840 Hui-Chun Xing http://orcid.org/0000-0002-9111-9669
Funding Agency and Grant Number	Funding Agency Grant Number National Key R&D Program of China 2022YFC2304500 and 2021YFC2301801 Beijing Municipal of Science and Technology Major Project Z221100007422002 Capital Funds for Health Improvement and Research CFH-2024-1-2181 Beijing Igandan Foundation iGandanF-1082023-GSH011
Corresponding Author	Hui-Chun Xing, Chief Physician, MD, PhD, Professor, Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, No. 8 Jingshun East Street, Chaoyang District, Beijing 100015, China. hchxing@sohu.com
Key Words	Chronic liver disease; Fecal microbiota transplantation; Intestinal microbiota; Liver-gut axis; Clinical efficacy
Core Tip	Fecal microbiota transplantation shows significant potential in treating chronic liver diseases by improving liver inflammation, biomarkers, lipid metabolism, and cognitive function. It works through the liver-gut axis, restoring intestinal microbiota balance. Despite promising results, challenges remain in donor selection, standard treatment protocols, and long-term safety. Ongoing clinical trials and further research are needed to refine protocols and establish standardized approaches for optimal efficacy and safety in managing chronic liver diseases.
Publish Date	2025-07-24 07:47
Citation	<p>Ma L, Zhang MH, Xu YF, Hao YX, Niu XX, Li Y, Xing HC. Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease. <i>World J Gastroenterol</i> 2025; 31(28): 105089</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i28/105089.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i28.105089

Full Article (PDF)	WJG-31-105089-with-cover.pdf
Manuscript File	105089_Auto_Edited_014538.docx
Answering Reviewers	105089-answering-reviewers.pdf
Audio Core Tip	105089-audio.mp3
Conflict-of-Interest Disclosure Form	105089-conflict-of-interest-statement.pdf
Copyright License Agreement	105089-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105089-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	105089-non-native-speakers.pdf
Supplementary Material	105089-supplementary-material.pdf
Peer-review Report	105089-peer-reviews.pdf
Scientific Misconduct Check	105089-scientific-misconduct-check.png
Scientific Editor Work List	105089-scientific-editor-work-list.pdf
CrossCheck Report	105089-crosscheck-report.pdf