Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	105140
Country	China

Received	2025-01-13 07:09
Peer-Review Started	2025-01-13 07:09
To Make the First Decision
Return for Revision	2025-03-19 03:14
Revised	2025-04-01 06:32
Second Decision	2025-04-22 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-22 07:25
Articles in Press	2025-04-22 07:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-03 03:49
Publish the Manuscript Online	2025-06-13 13:39

ISSN	1948-5204 (online)
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Category	Oncology
Manuscript Type	Review
Article Title	Role, mechanism, and application of N6-methyladenosine in hepatobiliary carcinoma
Manuscript Source	Invited Manuscript
All Author List	Chen Jia, Qing-Fu Lang, Zhi-Jie Yin, Jia Sun, Qing-Hui Meng and Tie-Min Pei
ORCID	Author(s) ORCID Number Tie-Min Pei http://orcid.org/0000-0002-0351-5400
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82172792
Corresponding Author	Tie-Min Pei, Chief Physician, Professor, Senior Researcher, Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin 150001, Heilongjiang Province, China. tiemin2008@163.com
Key Words	Hepatobiliary carcinoma; RNA modification; N6-methyladenosine; Therapeutic targets; Treatment
Core Tip	N6-methyladenine (m6A) modifications is one of the most common RNA modifications in eukaryotes, and it has been reported to affect biological process of cells via regulation of gene expression, and play a crucial role in occurrence and development in various cancers by regulating RNA stability, decay, spicing and transport. This article summarized the role and mechanism of m6A modification in hepatobiliary carcinoma, and discussed its potential clinical application in an attempt to provide theoretical evidences for the individualized treatment of hepatobiliary carcinoma.
Publish Date	2025-06-13 13:39
Citation	<p>Jia C, Lang QF, Yin ZJ, Sun J, Meng QH, Pei TM. Role, mechanism, and application of N6-methyladenosine in hepatobiliary carcinoma. <i>World J Gastrointest Oncol</i> 2025; 17(6): 105140</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i6/105140.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i6.105140

Full Article (PDF)	WJGO-17-105140-with-cover.pdf
Manuscript File	105140_Auto_Edited_031932.docx
Answering Reviewers	105140-answering-reviewers.pdf
Audio Core Tip	105140-audio.mp3
Conflict-of-Interest Disclosure Form	105140-conflict-of-interest-statement.pdf
Copyright License Agreement	105140-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105140-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	105140-non-native-speakers.pdf
Peer-review Report	105140-peer-reviews.pdf
Scientific Misconduct Check	105140-scientific-misconduct-check.png
Scientific Editor Work List	105140-scientific-editor-work-list.pdf
CrossCheck Report	105140-crosscheck-report.pdf