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8/18/2025 10:04:52 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 105229
Country China
Received
2025-01-16 03:09
Peer-Review Started
2025-01-16 03:10
To Make the First Decision
Return for Revision
2025-03-25 05:40
Revised
2025-04-08 05:40
Second Decision
2025-07-16 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-16 07:55
Articles in Press
2025-07-16 07:55
Publication Fee Transferred
2025-04-09 10:47
Edit the Manuscript by Language Editor
2025-07-21 22:31
Typeset the Manuscript
2025-08-08 01:40
Publish the Manuscript Online
2025-08-18 10:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Dynamic nomogram predicts sepsis risk in patients with acute liver failure: Analysis of intensive care database with external validation
Manuscript Source Unsolicited Manuscript
All Author List Rui Qi, Xin Wang, Zhi-Dan Kuang, Xue-Yi Shang, Fang Lin, Dan Chang and Jin-Song Mu
ORCID
Author(s) ORCID Number
Jin-Song Mu http://orcid.org/0000-0003-2892-1701
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Program 2022YFA1103501
Corresponding Author Jin-Song Mu, Associate Professor, Chief Physician, MD, PhD, /, Peking University 302 Clinical Medical School, No. 100 Xisihuan Middle Road, Fengtai District, Beijing 100039, China. jinsongmu302@126.com
Key Words Acute liver failure; Sepsis; Nomogram; Risk stratification; Predict
Core Tip The study developed and validated a dynamic nomogram to predict sepsis risk in acute liver failure patients using the Medical Information Mart for Intensive Care database (n = 510) and an external cohort (n = 228). Key predictors included age, total bilirubin, lactate dehydrogenase, albumin, and mechanical ventilation. The model demonstrated satisfactory accuracy (area under receiver operating characteristic curve = 0.849), outperformed Sequential Organ Failure Assessment and Systemic Inflammatory Response Syndrome scores. Decision curve analysis and calibration curves confirmed superior clinical utility and efficiency. The model-based risk stratification and online calculator might further facilitate risk evaluation and guide rational management.
Publish Date 2025-08-18 10:04
Citation <p>Qi R, Wang X, Kuang ZD, Shang XY, Lin F, Chang D, Mu JS. Dynamic nomogram predicts sepsis risk in patients with acute liver failure: Analysis of intensive care database with external validation. <i>World J Gastroenterol</i> 2025; 31(31): 105229</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i31/105229.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i31.105229
Full Article (PDF) WJG-31-105229-with-cover.pdf
Manuscript File 105229_Auto_Edited_010247.docx
Answering Reviewers 105229-answering-reviewers.pdf
Audio Core Tip 105229-audio.mp3
Biostatistics Review Certificate 105229-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105229-conflict-of-interest-statement.pdf
Copyright License Agreement 105229-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 105229-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s) 105229-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105229-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105229-non-native-speakers.pdf
Supplementary Material 105229-supplementary-material.pdf
Peer-review Report 105229-peer-reviews.pdf
Scientific Misconduct Check 105229-scientific-misconduct-check.png
Scientific Editor Work List 105229-scientific-editor-work-list.pdf
CrossCheck Report 105229-crosscheck-report.pdf