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Articles Published Processes
4/2/2025 10:54:13 AM | Browse: 23 | Download: 69
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Received |
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2025-01-16 03:47 |
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Peer-Review Started |
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2025-01-16 03:47 |
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To Make the First Decision |
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Return for Revision |
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2025-02-13 19:06 |
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Revised |
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2025-02-27 12:02 |
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Second Decision |
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2025-03-20 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-21 01:13 |
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Articles in Press |
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2025-03-21 01:13 |
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Publication Fee Transferred |
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2025-03-04 14:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-24 03:00 |
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Publish the Manuscript Online |
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2025-04-02 10:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Case Control Study |
| Article Title |
Altered microbiota of rectal mucosa in rectal cancer patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao Zhang, Yan Zhou, You-Heng Jiang, Wan-Ping Hu, Lu-Lu Huang, Hai-Xia Lin, Zhi-Gui Zuo, Ji-Mei Du and Yong-Liang Lou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Medical and Health Research Project of Zhejiang Province |
2023KY998 |
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| Corresponding Author |
Yong-Liang Lou, Professor, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Chashan Street, Wenzhou 325035, Zhejiang Province, China. lyl@wmu.edu.cn |
| Key Words |
Rectal cancer; Mucosal-associated microbiota; Gut microbiota; Genomics; Predictive biomarkers |
| Core Tip |
In this study, we focused on the rectal mucosal microbiota, which is associated with the occurrence and development of rectal cancer (RC). Although the gut microbiota is commonly studied in patients with colorectal cancer, but few studies have focused on RC, especially the microbiota of the rectal mucus. Our research revealed that RC patients had an altered rectal mucosal microbiota; characterized by enrichment of Bacteroidetes, Fusobacteria and Firmicutes; and depletion of Proteobacteria and Thermi. The Prevotella/Ruminococcus ratio and the Prevotella stercorea/Propionibacterium acnes in the rectal mucosal microbiota may serve as a marker for RC diagnosis. |
| Publish Date |
2025-04-02 10:54 |
| Citation |
<p>Zhang H, Zhou Y, Jiang YH, Hu WP, Huang LL, Lin HX, Zuo ZG, Du JM, Lou YL. Altered microbiota of rectal mucosa in rectal cancer patients. <i>World J Gastroenterol</i> 2025; 31(13): 105248</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i13/105248.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i13.105248 |
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