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Articles Published Processes
5/20/2025 3:37:29 AM | Browse: 224 | Download: 698
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Received |
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2025-01-20 10:34 |
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Peer-Review Started |
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2025-01-20 10:34 |
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First Decision by Editorial Office Director |
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2025-02-14 04:14 |
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Return for Revision |
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2025-02-14 04:14 |
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Revised |
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2025-02-27 09:18 |
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Publication Fee Transferred |
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2025-02-28 07:02 |
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Second Decision by Editor |
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2025-03-24 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-03-24 09:04 |
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Articles in Press |
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2025-03-24 09:04 |
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Edit the Manuscript by Language Editor |
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2025-03-25 15:05 |
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Typeset the Manuscript |
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2025-05-08 01:02 |
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Publish the Manuscript Online |
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2025-05-20 03:37 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Research & Experimental Medicine |
| Manuscript Type |
Basic Study |
| Article Title |
Natural compound rosmarinic acid displays anti-tumor activity in colorectal cancer cells by suppressing nuclear factor-kappa B signaling
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Yue Liu, Han Wang, Xin Xu, Xuan Wang, Kun-Kun Han, Wen-Dao You, Yili Yang and Tao Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Heilongjiang Province of China Under Grant |
PL2024H020 |
| High-Quality Innovation Platform of Science and Education Innovation Zone in Suzhou Industrial Park-Key Platform Project |
YZCXPT2023104 |
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| Corresponding Author |
Yili Yang, Professor, China Regional Research Center, International Centre for Genetic Engineering and Biotechnology, No. 8 Taohongjing Road, Taizhou 225300, Jiangsu Province, China. nathanyang@icgeb.cn |
| Key Words |
Rosmarinic acid; Colorectal cancer; Cell death; Nuclear factor-kappa B signaling; Chemotherapy |
| Core Tip |
Given the widespread use of rosmarinic acid (RA) as a food additive, this study aimed to investigate whether RA affected colorectal cancer (CRC) development. We verified that RA exerted its anti-tumor activity through effectively suppressing nuclear factor-kappaB signaling, and enhanced the cytotoxic actions of 5-fluorouracil and oxaliplatin in CRC cells, which indicated that RA might help to improve the chemotherapy of CRC. |
| Publish Date |
2025-05-20 03:37 |
| Citation |
Liu WY, Wang H, Xu X, Wang X, Han KK, You WD, Yang Y, Zhang T. Natural compound rosmarinic acid displays anti-tumor activity in colorectal cancer cells by suppressing nuclear factor-kappa B signaling. World J Clin Oncol 2025; 16(5): 105341 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i5/105341.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i5.105341 |
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