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Articles Published Processes
7/18/2025 3:29:29 PM | Browse: 6 | Download: 29
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Received |
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2025-01-20 10:44 |
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Peer-Review Started |
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2025-01-20 10:45 |
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To Make the First Decision |
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Return for Revision |
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2025-03-10 01:50 |
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Revised |
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2025-03-21 23:46 |
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Second Decision |
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2025-04-21 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-21 08:14 |
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Articles in Press |
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2025-04-21 08:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-03 01:54 |
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Publish the Manuscript Online |
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2025-07-18 15:29 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Methylene blue in the critical care setting
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Praveen Reddy Elmati, Teja Nagaradona, Vikas Raghove, Gowthami Sai Kogilathota Jagirdhar and Salim Surani |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Salim Surani, MD, Professor, Department of Medicine and Pharmacology, Texas AM University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com |
| Key Words |
Methylene blue; Critical care; Intensive care; Septic shock; Vasoplegic shock; Distributive shock |
| Core Tip |
Methylene blue is a promising medication with various benefits due to its inhibition of guanylate cyclase, anti-inflammatory effects, and nitric oxide inhibition. It has been researched in septic shock, distributive shock in cardiac procedures, anaphylaxis, and organ transplant procedures. It is a safe medication based on literature with rare documented adverse events at lower doses. Its role as an adjunct to vasopressors needs to be further researched, including the definition of the dose, initiation time, and usage duration. |
| Publish Date |
2025-07-18 15:29 |
| Citation |
<p>Elmati PR, Nagaradona T, Raghove V, Jagirdhar GSK, Surani S. Methylene blue in the critical care setting. <i>World J Crit Care Med</i> 2025; 14(3): 105350</p> |
| URL |
https://www.wjgnet.com/2220-3141/full/v14/i3/105350.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v14.i3.105350 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
