Publication Name	World Journal of Gastroenterology
Manuscript ID	105420
Country	China

Received	2025-01-22 10:34
Peer-Review Started	2025-01-22 10:35
To Make the First Decision
Return for Revision	2025-03-05 00:43
Revised	2025-03-05 04:04
Second Decision	2025-03-10 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-10 05:11
Articles in Press	2025-03-10 05:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-13 06:15
Publish the Manuscript Online	2025-04-11 02:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Gut microbiota plays a key role in the development of colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Ying-Ling Liu and Jie Liu
ORCID	Author(s) ORCID Number Ying-Ling Liu http://orcid.org/0009-0002-2149-4743 Jie Liu http://orcid.org/0000-0001-6079-7566
Funding Agency and Grant Number	Funding Agency Grant Number Research Project of the Chinese Digestive Early Cancer Physicians' Joint Growth Program GTCZ-2021-AH-34-0012
Corresponding Author	Jie Liu, MD, PhD, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. feixilj@163.com
Key Words	Colorectal cancer; Gut microbiota; Microbial dysbiosis; Intratumoral microbiota; Gut metabolites
Core Tip	Colorectal cancer (CRC) represents the most prevalent malignancy within the digestive system, characterized by elevated rates of mortality and morbidity. In this letter, we provide commentary on the research conducted by Darnindro et al, which identified the four most dominant phyla present in their study as Firmicutes, Proteobacteria, Bacteroidetes, and Fusobacteria. Importantly, the study revealed a significant disparity in beta diversity at both the genus and species levels when comparing groups with CRC to those without.
Publish Date	2025-04-11 02:19
Citation	<p>Liu YL, Liu J. Gut microbiota plays a key role in the development of colorectal cancer. <i>World J Gastroenterol</i> 2025; 31(14): 105420</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i14/105420.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i14.105420

Full Article (PDF)	WJG-31-105420-with-cover.pdf
Manuscript File	105420_Auto_Edited_122613.docx
Answering Reviewers	105420-answering-reviewers.pdf
Audio Core Tip	105420-audio.m4a
Conflict-of-Interest Disclosure Form	105420-conflict-of-interest-statement.pdf
Copyright License Agreement	105420-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105420-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	105420-non-native-speakers.pdf
Peer-review Report	105420-peer-reviews.pdf
Scientific Misconduct Check	105420-scientific-misconduct-check.png
Scientific Editor Work List	105420-scientific-editor-work-list.pdf
CrossCheck Report	105420-crosscheck-report.pdf