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Articles Published Processes
7/14/2025 12:56:05 PM | Browse: 11 | Download: 38
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Received |
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2025-04-15 09:40 |
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Peer-Review Started |
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2025-04-15 09:40 |
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To Make the First Decision |
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Return for Revision |
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2025-04-28 08:45 |
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Revised |
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2025-05-16 06:39 |
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Second Decision |
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2025-06-18 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-18 06:58 |
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Articles in Press |
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2025-06-18 06:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-30 02:00 |
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Publish the Manuscript Online |
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2025-07-14 12:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Correlation of serum cytokine-induced neutrophil chemoattractant levels with Helicobacter pylori infection and disease severity in gastric cancer patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Ling Zhang, Xiao-Lei Niu and Ning Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hebei Province Medical Science Research Project Plan |
20210923 |
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| Corresponding Author |
Ning Wang, Department of Gastroenterology, Shijiazhuang People's Hospital, No. 365 Jianhua South Street, Yuhua District, Shijiazhuang 050000, Hebei Province, China. zhangniuxh@163.com |
| Key Words |
Gastric cancer; Helicobacter pylori; Cytokine-induced neutrophil chemoattractant; Inflammation; Prognosis |
| Core Tip |
This study reveals that Helicobacter pylori (H. pylori) infection significantly elevates serum cytokine-induced neutrophil chemoattractant (CINC) levels in gastric cancer patients, particularly in those infected with cytotoxin-associated gene A/vacuolating cytotoxin-positive strains. CINC levels correlate with advanced TNM staging and independently predict poor survival, highlighting its role as a novel prognostic biomarker. Longitudinal monitoring demonstrates dynamic CINC changes aligned with disease progression, suggesting utility in treatment response assessment. These findings position CINC-driven neutrophilic inflammation as a therapeutic target and underscore the synergy between H. pylori virulence factors and systemic inflammation in accelerating gastric carcinogenesis. |
| Publish Date |
2025-07-14 12:56 |
| Citation |
<p>Zhang HL, Niu XL, Wang N. Correlation of serum cytokine-induced neutrophil chemoattractant levels with Helicobacter pylori infection and disease severity in gastric cancer patients. <i>World J Gastrointest Oncol</i> 2025; 17(7): 105455</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i7/105455.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i7.105455 |
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