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Articles Published Processes
8/4/2025 12:11:18 PM | Browse: 6 | Download: 23
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Received |
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2025-01-23 10:41 |
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Peer-Review Started |
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2025-01-23 10:42 |
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To Make the First Decision |
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Return for Revision |
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2025-03-11 12:31 |
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Revised |
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2025-03-21 13:29 |
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Second Decision |
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2025-04-03 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-03 08:09 |
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Articles in Press |
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2025-04-03 08:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-08 02:30 |
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Publish the Manuscript Online |
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2025-08-04 12:11 |
ISSN |
2222-0682 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Role of irisin in physical activity, sarcopenia-associated type 2 diabetes, and cardiovascular complications
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Manuscript Source |
Invited Manuscript |
All Author List |
Maja Cigrovski Berkovic, Vjekoslav Cigrovski and Lana Ruzic |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Maja Cigrovski Berkovic, Associate Professor, MD, PhD, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Horvacanski zavoj 15, Zagreb 10000, Croatia. maja.cigrovskiberkovic@gmail.com |
Key Words |
Type 2 diabetes mellitus; Exercise; Myokines; Irisin; Sarcopenia; Vascular complications |
Core Tip |
Physical inactivity, sarcopenia, and diabetes are interrelated conditions, each exacerbating the others. The impact of these issues is significant, particularly on the cardiovascular system. Irisin, a myokine with autocrine, paracrine, and endocrine functions, may play a key role in metabolic health and could serve as an adjunct to the pharmacological management of prediabetes and diabetes. The exact mechanisms through which irisin exerts its beneficial effects, and the optimal levels for the therapeutic potential, need further investigation. Moreover, assessing irisin levels in response to different exercise types and intensities could be valuable in customizing individualized exercise plans for patients with diabetes and related complications. |
Publish Date |
2025-08-04 12:11 |
Citation |
<p>Cigrovski Berkovic M, Cigrovski V, Ruzic L. Role of irisin in physical activity, sarcopenia-associated type 2 diabetes, and cardiovascular complications. <i>World J Methodol</i> 2025; 15(4): 105462</p> |
URL |
https://www.wjgnet.com/2222-0682/full/v15/i4/105462.htm |
DOI |
https://dx.doi.org/10.5662/wjm.v15.i4.105462 |
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