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8/4/2025 12:11:32 PM | Browse: 13 | Download: 41
Publication Name World Journal of Methodology
Manuscript ID 105493
Country United Kingdom
Received
2025-01-24 06:57
Peer-Review Started
2025-01-24 06:57
To Make the First Decision
Return for Revision
2025-03-16 12:13
Revised
2025-03-29 12:17
Second Decision
2025-05-06 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-07 10:27
Articles in Press
2025-05-07 10:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-07-07 05:39
Publish the Manuscript Online
2025-08-04 12:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Retrospective Study
Article Title Machine learning for patient selection in corticosteroid decision making in knee osteoarthritis: A feasibility model
Manuscript Source Unsolicited Manuscript
All Author List Omar Musbahi, Kyriacos Pouris, Savvas Hadjixenophontos, Ahmed Al-Saadawi, Iris Soteriou, Justin Peter Cobb and Gareth G Jones
ORCID
Author(s) ORCID Number
Omar Musbahi http://orcid.org/0000-0002-4095-0989
Funding Agency and Grant Number
Funding Agency Grant Number
National Institute For Health and Care Research No. NIHR302632
Corresponding Author Omar Musbahi, Senior Researcher, Department of Surgery and Cancer - Faculty of Medicine, Imperial College London, 86 Wood Ln, London W12 0BZ, United Kingdom. om112@ic.ac.uk
Key Words Knee osteoarthritis; Machine learning; Predictive modelling; Corticosteroid injection; Patient selection
Core Tip Historically, the efficacy of corticosteroid injections in knee osteoarthritis has been heavily debated, as patient responses can vary significantly. This study evaluates the feasibility of a machine learning model to identify which patients with knee osteoarthritis will benefit from corticosteroid injections. Data from two cohort studies were combined for analysis. The model generated an accuracy of 67.8% (95% confidence interval: 64.6%-70.9%), F1 score of 30.8%, and an area under the curve score of 0.60. These metrics demonstrate feasibility to assist clinicians with decision-making in patient selection for corticosteroid injections. Further research is required to improve the model prior to testing in clinical settings.
Publish Date 2025-08-04 12:11
Citation <p>Musbahi O, Pouris K, Hadjixenophontos S, Al-Saadawi A, Soteriou I, Cobb JP, Jones GG. Machine learning for patient selection in corticosteroid decision making in knee osteoarthritis: A feasibility model. <i>World J Methodol</i> 2025; 15(4): 105493</p>
URL https://www.wjgnet.com/2222-0682/full/v15/i4/105493.htm
DOI https://dx.doi.org/10.5662/wjm.v15.i4.105493
Full Article (PDF) WJM-15-105493-with-cover.pdf
Manuscript File 105493_Auto_Edited_062653.docx
Answering Reviewers 105493-answering-reviewers.pdf
Audio Core Tip 105493-audio.m4a
Biostatistics Review Certificate 105493-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105493-conflict-of-interest-statement.pdf
Copyright License Agreement 105493-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 105493-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105493-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105493-non-native-speakers.pdf
Peer-review Report 105493-peer-reviews.pdf
Scientific Misconduct Check 105493-scientific-misconduct-check.png
Scientific Editor Work List 105493-scientific-editor-work-list.pdf
CrossCheck Report 105493-crosscheck-report.pdf