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Articles Published Processes
10/1/2014 8:25:00 PM | Browse: 1302 | Download: 1456
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Received |
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2014-04-07 11:25 |
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Peer-Review Started |
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2014-04-07 11:50 |
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To Make the First Decision |
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2014-05-20 11:12 |
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Return for Revision |
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2014-05-20 11:44 |
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Revised |
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2014-06-08 13:12 |
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Second Decision |
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2014-06-26 17:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-06-26 17:15 |
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Articles in Press |
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2014-06-26 17:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-07-19 17:20 |
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Typeset the Manuscript |
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2014-09-11 15:33 |
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Publish the Manuscript Online |
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2014-10-01 20:25 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Clinical Trials Study |
Article Title |
Negative methylation status of Vimentin predicts improved prognosis in pancreatic carcinoma
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yi-Feng Zhou, Wei Xu, Xia Wang, Jin-Shan Sun, Jing-Jing Xiang, Zhao-Shen Li and Xiao-Feng Zhang |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81001078 |
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Corresponding Author |
Dr. Xiao-Feng Zhang, Department of Digestive Medicine, The First People’s Hospital of Hangzhou, Huansha Road 261, Hangzhou 310006, Zhejiang Province, China. zxf837@tom.com |
Key Words |
Vimentin; Methylation; Pancreatic carcinoma; Prognosis |
Core Tip |
Vimentin is reported to be an important mesenchymal marker, and plays an important role in epithelial-mesenchymal transition in malignant tumors with regard to cellular adhesion, migration and signaling. In our study, we found that pathological T staging (P < 0.001), adjuvant chemotherapy (P = 0.003) and the Vimentin gene methylation state (P = 0.037) were independent prognostic factors. However, additional experiments and clinical trials are needed to accurately validate this observation. |
Publish Date |
2014-10-01 20:25 |
Citation |
Zhou YF, Xu W, Wang X, Sun JS, Xiang JJ, Li ZS, Zhang XF. Negative methylation status of Vimentin predicts improved prognosis in pancreatic carcinoma. World J Gastroenterol 2014; 20(36): 13172-13177 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i36/13172.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i36.13172 |
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