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4/14/2025 7:02:36 AM | Browse: 27 | Download: 24
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 105630
Country United States
Received
2025-02-02 04:59
Peer-Review Started
2025-02-02 04:59
To Make the First Decision
Return for Revision
2025-03-12 08:35
Revised
2025-03-16 17:38
Second Decision
2025-04-02 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-02 06:32
Articles in Press
2025-04-02 06:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-09 02:55
Publish the Manuscript Online
2025-04-14 07:02
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title Endoscopic intervention in hematologic malignancy patients with severe thrombocytopenia: Methodological concerns, clinical implications, and future research directions
Manuscript Source Invited Manuscript
All Author List Arunkumar Krishnan
ORCID
Author(s) ORCID Number
Arunkumar Krishnan http://orcid.org/0000-0002-9452-7377
Funding Agency and Grant Number
Corresponding Author Arunkumar Krishnan, Associate Professor, MD, Senior Researcher, Department of Supportive Oncology, Atrium Health Levine Cancer, 1021 Morehead Medical Drive, Suite 70100, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com
Key Words Gastrointestinal bleeding; Thrombocytopenia; Hematologic malignancies; Endoscopic intervention; Clinical outcomes; Hemostatic management
Core Tip Endoscopic intervention for gastrointestinal bleeding in patients with severe thrombocytopenia is debated due to the lack of standardized platelet thresholds and procedural risks. A recent study by Alhumayyd et al highlighted these challenges but was limited by small sample sizes, retrospective design, and inadequate adjustment for confounders. Key factors like hemodynamic stability, hematologic malignancy severity, and platelet function assessments were insufficiently addressed. Variations in endoscopic timing and hemostasis techniques further complicate results. Prospective, multicenter studies incorporating platelet function assays and standardized protocols are essential to improve gastrointestinal bleeding management in thrombocytopenic patients.
Publish Date 2025-04-14 07:02
Citation <p>Krishnan A. Endoscopic intervention in hematologic malignancy patients with severe thrombocytopenia: Methodological concerns, clinical implications, and future research directions. <i>World J Gastrointest Endosc</i> 2025; 17(4): 105630</p>
URL https://www.wjgnet.com/1948-5190/full/v17/i4/105630.htm
DOI https://dx.doi.org/10.4253/wjge.v17.i4.105630
Full Article (PDF) WJGE-17-105630-with-cover.pdf
Manuscript File 105630_Auto_Edited_014618.docx
Answering Reviewers 105630-answering-reviewers.pdf
Audio Core Tip 105630-audio.mp4
Conflict-of-Interest Disclosure Form 105630-conflict-of-interest-statement.pdf
Copyright License Agreement 105630-copyright-assignment.pdf
Peer-review Report 105630-peer-reviews.pdf
Scientific Misconduct Check 105630-scientific-misconduct-check.png
Scientific Editor Work List 105630-scientific-editor-work-list.pdf
CrossCheck Report 105630-crosscheck-report.pdf