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4/16/2025 5:36:40 AM | Browse: 9 | Download: 21
Publication Name World Journal of Experimental Medicine
Manuscript ID 105636
Country India
Received
2025-02-02 05:44
Peer-Review Started
2025-02-02 05:44
To Make the First Decision
Return for Revision
2025-02-20 04:09
Revised
2025-03-03 16:19
Second Decision
2025-03-14 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-14 09:07
Articles in Press
2025-03-14 09:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-08 01:11
Publish the Manuscript Online
2025-04-16 05:36
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dentistry, Oral Surgery & Medicine
Manuscript Type Clinical Trials Study
Article Title Evaluation of the clinical efficacy of green tea extract gel as local drug delivery for periodontitis
Manuscript Source Invited Manuscript
All Author List Santhiya Rengaraj, Sri Sivashankari Thilagar, Pradeep Kumar Yadalam, Priyanka Pampani, Ebenezer Mani and Carlos M Ardila
ORCID
Author(s) ORCID Number
Pradeep Kumar Yadalam http://orcid.org/0000-0002-6653-4123
Carlos M Ardila http://orcid.org/0000-0002-3663-1416
Funding Agency and Grant Number
Corresponding Author Carlos M Ardila, Postdoctoral Fellow, Professor, Senior Researcher, Basic Sciences Department, Biomedical Stomatology Research Group, Faculty of Dentistry, Universidad de Antioquia, U de A, Calle 70 No. 52-21, Medellin 050010, Antioquia, Colombia. martin.ardila@udea.edu.co
Key Words Periodontitis; Ornidazole; Green tea; Local drug delivery; Treatment
Core Tip Green tea extract gel, rich in epigallocatechin gallate, outperformed ornidazole gel as an adjunct to scaling and root planing in treating periodontitis, demonstrating superior reduction in probing pocket depths after one month. This study highlights green tea extract’s potential as a natural, effective alternative for localized antimicrobial therapy, offering enhanced anti-inflammatory and antimicrobial benefits for periodontal disease management. Its promising results suggest a shift toward plant-based adjuncts in periodontal care.
Publish Date 2025-04-16 05:36
Citation <p>Rengaraj S, Thilagar SS, Yadalam PK, Pampani P, Mani E, Ardila CM. Evaluation of the clinical efficacy of green tea extract gel as local drug delivery for periodontitis. <i>World J Exp Med</i> 2025; 15(2): 105636</p>
URL https://www.wjgnet.com/2220-315x/full/v15/i2/105636.htm
DOI https://dx.doi.org/10.5493/wjem.v15.i2.105636
Full Article (PDF) WJEM-15-105636-with-cover.pdf
CONSORT 2010 Statement 105636-CONSORT-2010-statement.pdf
Manuscript File 105636_Auto_Edited_032909.docx
Answering Reviewers 105636-answering-reviewers.pdf
Audio Core Tip 105636-audio.m4a
Biostatistics Review Certificate 105636-biostatistics-statement.pdf
Clinical Trial Registration Statement 105636-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 105636-conflict-of-interest-statement.pdf
Copyright License Agreement 105636-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 105636-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105636-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105636-non-native-speakers.pdf
Peer-review Report 105636-peer-reviews.pdf
Scientific Misconduct Check 105636-scientific-misconduct-check.png
Scientific Editor Work List 105636-scientific-editor-work-list.pdf
CrossCheck Report 105636-crosscheck-report.pdf