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Articles Published Processes
6/13/2025 1:39:46 PM | Browse: 30 | Download: 253
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Received |
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2025-02-10 07:11 |
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Peer-Review Started |
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2025-02-10 07:11 |
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To Make the First Decision |
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Return for Revision |
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2025-03-19 03:23 |
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Revised |
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2025-03-25 04:57 |
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Second Decision |
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2025-05-12 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-12 10:25 |
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Articles in Press |
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2025-05-12 10:25 |
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Publication Fee Transferred |
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2025-03-29 11:17 |
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Edit the Manuscript by Language Editor |
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2025-05-19 06:22 |
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Typeset the Manuscript |
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2025-05-30 02:24 |
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Publish the Manuscript Online |
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2025-06-13 13:39 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
RPF2 regulates the protein kinase B/mammalian target of rapamycin pathway in the pathogenesis of Helicobacter pylori and its mechanism
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Qiao Hua, Kai-Xin Guo, Peng Ni, Di Wang, Tong-Yan An, Yang-Ye Gao and Rong-Guang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82160634 |
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| Corresponding Author |
Rong-Guang Zhang, MD, Professor, Department of Epidemiology, College of Public Health, Zhengzhou University, No. 100 Science Avenue, Zhongyuan District, Zhengzhou 450001, Henan Province, China. zrg@zzu.edu.cn |
| Key Words |
RPF2; Helicobacter pylori; Epithelial-mesenchymal transition; Protein kinase B/mammalian target of rapamycin pathway; Gastric cancer |
| Core Tip |
Helicobacter pylori (H. pylori) has a profound impact on the development of gastric cancer. It has been demonstrated that RPF2 is overexpressed in cancer and can enhance the proliferation of cancer cells. However, the mechanism of RPF2 in the pathogenesis of H. pylori infection remains largely unknown. We found that H. pylori infection increased the expression of RPF2, and RPF2 affected the malignant behavior of gastric epithelial cells by regulating the protein kinase B/mammalian target of rapamycin pathway. This study is the first to explore the mechanism of RPF2 in the pathogenesis of H. pylori infection. |
| Publish Date |
2025-06-13 13:39 |
| Citation |
<p>Hua YQ, Guo KX, Ni P, Wang D, An TY, Gao YY, Zhang RG. RPF2 regulates the protein kinase B/mammalian target of rapamycin pathway in the pathogenesis of Helicobacter pylori and its mechanism. <i>World J Gastrointest Oncol</i> 2025; 17(6): 105664</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/105664.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.105664 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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