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5/27/2025 7:04:46 AM | Browse: 3 | Download: 23
Publication Name World Journal of Hepatology
Manuscript ID 105706
Country United Kingdom
Received
2025-02-04 19:31
Peer-Review Started
2025-02-04 19:31
To Make the First Decision
Return for Revision
2025-03-21 07:59
Revised
2025-03-31 15:06
Second Decision
2025-04-22 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-22 10:45
Articles in Press
2025-04-22 10:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-14 02:36
Publish the Manuscript Online
2025-05-27 07:04
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Systematic Reviews
Article Title Cardiovascular implications of metabolic dysfunction-associated fatty liver disease and type 2 diabetes mellitus: A meta-analysis
Manuscript Source Invited Manuscript
All Author List Sahana Shetty, Renuka Suvarna, Vanessa Ambrose Fistus, Shivam Modi and Joseph M Pappachan
ORCID
Author(s) ORCID Number
Sahana Shetty http://orcid.org/0000-0003-0851-0411
Joseph M Pappachan http://orcid.org/0000-0003-0886-5255
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, MD, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, Manchester, Manchester M15 6BH, Please enter the state or province, United Kingdom. drpappachan@yahoo.co.in
Key Words Cardiovascular disease; Cardiovascular events; Insulin resistance; Metabolic dysfunction-associated fatty liver disease; Type 2 diabetes mellitus.
Core Tip Metabolic dysfunction-associated fatty liver disease (MAFLD) and type 2 diabetes mellitus (T2DM) are independent risk factors for the development of cardiovascular disease (CVD) with an exaggerated risk of cardiovascular events (CVE) when both diseases co-exist. A systematic review of fourteen studies with 370013 participants showed that the risk of CVE in T2DM was higher in the MAFLD group when compared to the non-MAFLD group [odds ratios (OR): 1.28] with follow up duration ranging between 5-6 years. The prevalence of CVD was higher (OR: 1.47) in T2DM with MAFLD when compared to T2DM without MAFLD. In conclusion, presence of MAFLD in T2DM increased the risk of CVE and CVD as compared to T2DM without MAFLD.
Publish Date 2025-05-27 07:04
Citation <p>Shetty S, Suvarna R, Ambrose Fistus V, Modi S, Pappachan JM. Cardiovascular implications of metabolic dysfunction-associated fatty liver disease and type 2 diabetes mellitus: A meta-analysis. <i>World J Hepatol</i> 2025; 17(5): 105706</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i5/105706.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i5.105706
Full Article (PDF) WJH-17-105706-with-cover.pdf
PRISMA 2009 Checklist 105706-PRISMA-2009-Checklist.pdf
Manuscript File 105706_Auto_Edited_032312.docx
Answering Reviewers 105706-answering-reviewers.pdf
Audio Core Tip 105706-audio.m4a
Biostatistics Review Certificate 105706-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105706-conflict-of-interest-statement.pdf
Copyright License Agreement 105706-copyright-assignment.pdf
Supplementary Material 105706-supplementary-material.pdf
Peer-review Report 105706-peer-reviews.pdf
Scientific Misconduct Check 105706-scientific-misconduct-check.png
Scientific Editor Work List 105706-scientific-editor-work-list.pdf
CrossCheck Report 105706-crosscheck-report.pdf