Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	105712
Country	China

Received	2025-02-05 04:39
Peer-Review Started	2025-02-05 04:39
To Make the First Decision
Return for Revision	2025-03-25 07:10
Revised	2025-04-04 08:55
Second Decision	2025-05-30 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-30 07:25
Articles in Press	2025-05-30 07:25
Publication Fee Transferred	2025-04-11 04:31
Edit the Manuscript by Language Editor	2025-06-04 18:36
Typeset the Manuscript	2025-06-30 01:58
Publish the Manuscript Online	2025-07-14 12:55

ISSN	1948-5204 (online)
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Progress in the treatment of duodenal cancer: A comprehensive review
Manuscript Source	Unsolicited Manuscript
All Author List	Liang-Gong Liao, Zhi-Guo Xiong and Jun-Jie Hu
ORCID	Author(s) ORCID Number Jun-Jie Hu http://orcid.org/0009-0007-5411-3755
Funding Agency and Grant Number	Funding Agency Grant Number Research Projects of Biomedical Center of Hubei Cancer Hospital 2022SWZX07 the 2023-2024 Annual Scientific Research Project of Traditional Chinese Medicine from Hubei Provincial Administration of Traditional Chinese Medicine ZY2023Z005 Health Commission of Hubei Province Scientific Research Project WJ2023Z011
Corresponding Author	Jun-Jie Hu, MD, Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 116 Zuodaoquan South Road, Wuhan 430079, Hubei Province, China. 791462122@qq.com
Key Words	Immunotherapy; Targeted therapies; Chemotherapy; Surgical resection; Duodenal cancer
Core Tip	Duodenal cancer, a rare gastrointestinal malignancy (< 0.5/100000 incidence), requires multidisciplinary strategies. Endoscopic resection for early-stage tumors improves survival and reduces infection mortality. Advanced cases benefit from surgery and minimally invasive techniques. Chemotherapy and neoadjuvant chemoradiotherapy enhance outcomes. Targeted therapies such as erb-b2 receptor tyrosine kinase 2 (human epidermal growth factor receptor 2)/phosphatidylinositol-3-kinase inhibitors and immunotherapy show transformative potential. Molecular profiling guides precision medicine. International collaboration is critical to optimize biomarker-driven strategies and improve survival. This review integrates innovations in surgery, systemic therapy, and immunotherapy, offering a roadmap for personalized management.
Publish Date	2025-07-14 12:55
Citation	<p>Liao LG, Xiong ZG, Hu JJ. Progress in the treatment of duodenal cancer: A comprehensive review. <i>World J Gastrointest Oncol</i> 2025; 17(7): 105712</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i7/105712.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i7.105712

Full Article (PDF)	WJGO-17-105712-with-cover.pdf
Manuscript File	105712_Auto_Edited_060244.docx
Answering Reviewers	105712-answering-reviewers.pdf
Audio Core Tip	105712-audio.m4a
Conflict-of-Interest Disclosure Form	105712-conflict-of-interest-statement.pdf
Copyright License Agreement	105712-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105712-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	105712-non-native-speakers.pdf
Peer-review Report	105712-peer-reviews.pdf
Scientific Misconduct Check	105712-scientific-misconduct-check.png
Scientific Editor Work List	105712-scientific-editor-work-list.pdf
CrossCheck Report	105712-crosscheck-report.pdf