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4/22/2025 6:49:49 AM | Browse: 89 | Download: 297
Publication Name World Journal of Radiology
Manuscript ID 105722
Country China
Received
2025-02-05 04:16
Peer-Review Started
2025-02-05 04:16
First Decision by Editorial Office Director
2025-02-24 08:18
Return for Revision
2025-02-24 08:18
Revised
2025-03-09 15:16
Publication Fee Transferred
Second Decision by Editor
2025-03-25 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-03-25 07:18
Articles in Press
2025-03-25 07:18
Edit the Manuscript by Language Editor
2025-03-27 04:43
Typeset the Manuscript
2025-04-21 03:28
Publish the Manuscript Online
2025-04-22 06:49
ISSN 1949-8470 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Clinical translation of ultra-high dose rate flash radiotherapy: Opportunities, challenges, and prospects
Manuscript Source Invited Manuscript
All Author List Xiang-Xiang Yang, Hui Luo, Jia-Jun Zhang, Hong Ge and Liang Ge
ORCID
Author(s) ORCID Number
Hong Ge http://orcid.org/0000-0003-4270-2556
Liang Ge http://orcid.org/0009-0006-0999-6483
Funding Agency and Grant Number
Corresponding Author Liang Ge, Assistant Professor, MD, PhD, Department of Medical Imaging, The Fifth Affiliated Hospital of Zhengzhou University, No. 3 Kangfuqian Street, Zhengzhou 450001, Henan Province, China. zl13703920959@sina.com
Key Words Ultra-high dose rate flash radiotherapy; Mechanism; Clinical translation; Radiation-induced damage to normal tissues; Prospects
Core Tip Ultra-high dose rate flash radiotherapy (FLASH-RT) has garnered significant attention due to its unique high-efficiency and low-toxicity biological effects. With an increasing number of research teams entering this field, the number of related publications has grown exponentially. While the high-efficiency and low-toxicity characteristics of FLASH-RT have been extensively validated, it is equally crucial to objectively analyze relevant negative findings. This article systematically synthesizes published research data to elucidate the advance of FLASH-RT. These findings provide valuable references for designing future FLASH-RT preclinical experimental protocols and facilitating clinical translation.
Publish Date 2025-04-22 06:49
Citation

Yang XX, Luo H, Zhang JJ, Ge H, Ge L. Clinical translation of ultra-high dose rate flash radiotherapy: Opportunities, challenges, and prospects. World J Radiol 2025; 17(4): 105722

URL https://www.wjgnet.com/1949-8470/full/v17/i4/105722.htm
DOI https://dx.doi.org/10.4329/wjr.v17.i4.105722
Full Article (PDF) WJR-17-105722-with-cover.pdf
Manuscript File 105722-Review-FilipodiaCL.docx
Answering Reviewers 105722-answering-reviewers.pdf
Audio Core Tip 105722-audio.mp3
Conflict-of-Interest Disclosure Form 105722-conflict-of-interest-statement.pdf
Copyright License Agreement 105722-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 105722-non-native-speakers.pdf
Peer-review Report 105722-peer-reviews.pdf
Scientific Misconduct Check 105722-scientific-misconduct-check.png
Scientific Editor Work List 105722-scientific-editor-work-list.pdf
CrossCheck Report 105722-crosscheck-report.pdf