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Articles Published Processes
7/14/2025 12:55:57 PM | Browse: 6 | Download: 31
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Received |
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2025-02-05 04:17 |
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Peer-Review Started |
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2025-02-05 04:18 |
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To Make the First Decision |
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Return for Revision |
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2025-03-27 09:43 |
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Revised |
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2025-05-01 08:23 |
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Second Decision |
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2025-06-05 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-05 08:03 |
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Articles in Press |
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2025-06-05 08:03 |
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Publication Fee Transferred |
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2025-05-08 08:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-30 02:01 |
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Publish the Manuscript Online |
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2025-07-14 12:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Neutrophil extracellular traps predict sensitivity to neoadjuvant chemotherapy combined with immunotherapy in locally advanced gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan Lv, Wei-Xuan Li, Liang Sun, Lin-Pu Xin, Tao Li, Wen-Tao Zhong, Hong-Yan Zhu, Ran An, Ai-Jun Liu and Lin Chen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lin Chen, Assistant Professor, Medical School of Chinese PLA, No. 28 FuXinglu, Haidian District, Beijing 100089, China. chenlinbj301@163.com |
| Key Words |
Neutrophil extracellular traps; Locally advanced gastric cancer; Neoadjuvant chemotherapy; Neoadjuvant immunotherapy; Treatment sensitivity |
| Core Tip |
This study identified neutrophil extracellular traps (NETs) as a novel prognostic and predictive biomarker for neoadjuvant chemotherapy combined with immunotherapy (NACI) in locally advanced gastric cancer (LAGC). Low pretreatment NET density correlated with higher pathological complete response and overall response rates, while increased post-treatment NET density was associated with poorer outcomes. These findings suggest that targeting NET formation could enhance NACI efficacy, offering a potential therapeutic strategy for LAGC patients. |
| Publish Date |
2025-07-14 12:55 |
| Citation |
<p>Lv Y, Li WX, Sun L, Xin LP, Li T, Zhong WT, Zhu HY, An R, Liu AJ, Chen L. Neutrophil extracellular traps predict sensitivity to neoadjuvant chemotherapy combined with immunotherapy in locally advanced gastric cancer. <i>World J Gastrointest Oncol</i> 2025; 17(7): 105723</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i7/105723.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i7.105723 |
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