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8/14/2025 5:49:33 AM | Browse: 57 | Download: 213
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 105818
Country China
Received
2025-04-25 08:00
Peer-Review Started
2025-04-25 08:00
First Decision by Editorial Office Director
2025-05-17 03:37
Return for Revision
2025-05-17 03:37
Revised
2025-05-29 17:08
Publication Fee Transferred
2025-05-31 18:35
Second Decision by Editor
2025-07-01 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-07-01 07:38
Articles in Press
2025-07-01 07:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-01 01:32
Publish the Manuscript Online
2025-08-14 05:49
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Contrast-enhanced ultrasound in evaluating the curative effect of interventional therapy in patients with liver cancer
Manuscript Source Unsolicited Manuscript
All Author List Li-Ping Chen, Yan Dong, Jing-Guang He, Qing-Qing Yang and Zhi-Wen Hu
ORCID
Author(s) ORCID Number
Li-Ping Chen http://orcid.org/0000-0002-4736-2952
Zhi-Wen Hu http://orcid.org/0000-0002-3472-6083
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Program of Guangzhou No. 2024A03J1029
Science and Technology Program of Chinese Medicine and Integrated Chinese and Western Medicine in Guangzhou No. 20252A010001
Corresponding Author Zhi-Wen Hu, MD, Department of Medical Ultrasound, Guangzhou First People's Hospital, No.1 Panfu Road, Guangzhou 510180, Guangdong Province, China. charleyhu@163.com
Key Words Contrast-enhanced ultrasound; Liver cancer; Interventional therapy; Blood perfusion; Tumor microvessel density; Tumor markers; Alpha-fetoprotein; Perfusion recovery; Receiver operating characteristic curve
Core Tip This observational study highlights the value of contrast-enhanced ultrasonography (CEUS) in evaluating the therapeutic response of liver cancer patients to interventional therapy. CEUS enables real-time visualization of tumor perfusion patterns, microvessel density changes, and alterations in tumor markers. Among 124 patients, CEUS demonstrated high sensitivity (85.72%) and specificity (92.31%) in assessing treatment efficacy. Notably, tumor blood flow and tumor marker levels (alpha-fetoprotein, carcinoembryonic antigen, carbohydrate antigen 19-9) significantly decreased post-treatment. These findings support CEUS as a reliable, noninvasive tool for monitoring treatment outcomes and guiding clinical decision-making in liver cancer management.
Publish Date 2025-08-14 05:49
Citation

Chen LP, Dong Y, He JG, Yang QQ, Hu ZW. Contrast-enhanced ultrasound in evaluating the curative effect of interventional therapy in patients with liver cancer. World J Gastrointest Oncol 2025; 17(8): 105818

URL https://www.wjgnet.com/1948-5204/full/v17/i8/105818.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i8.105818
Full Article (PDF) WJGO-17-105818-with-cover.pdf
STROBE Statement 105818-STROBE-statement.pdf
Manuscript File 105818_Auto_Edited_012849.docx
Answering Reviewers 105818-answering-reviewers.pdf
Audio Core Tip 105818-audio.mp3
Biostatistics Review Certificate 105818-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105818-conflict-of-interest-statement.pdf
Copyright License Agreement 105818-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 105818-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105818-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105818-non-native-speakers.pdf
Peer-review Report 105818-peer-reviews.pdf
Scientific Misconduct Check 105818-scientific-misconduct-check.png
Scientific Editor Work List 105818-scientific-editor-work-list.pdf
CrossCheck Report 105818-crosscheck-report.pdf