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Articles Published Processes
6/6/2025 3:09:39 AM | Browse: 3 | Download: 32
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Received |
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2025-02-10 05:07 |
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Peer-Review Started |
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2025-02-10 05:07 |
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To Make the First Decision |
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Return for Revision |
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2025-03-26 03:06 |
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Revised |
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2025-04-05 15:45 |
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Second Decision |
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2025-05-21 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-21 05:22 |
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Articles in Press |
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2025-05-21 05:22 |
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Publication Fee Transferred |
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2025-04-07 13:06 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-30 09:14 |
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Publish the Manuscript Online |
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2025-06-06 03:09 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Retrospective Study |
| Article Title |
Longitudinal computed tomography-based delta-radiomics of visceral adipose tissue predicts infliximab secondary loss of response in Crohn’s disease patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xi Li, Fu-Long Song, Hai-Feng He, Shu-Min Zeng, Zhi-Chao Feng and Peng-Fei Rong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
82372072 and 82071986 |
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| Corresponding Author |
Peng-Fei Rong, Department of Radiology, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Changsha 410013, Hunan Province, China. rongpengfei66@163.com |
| Key Words |
Crohn’s disease; Computed tomography enterography; Infliximab; Delta-radiomics; Secondary loss of response |
| Core Tip |
The treatment response to infliximab in patients with Crohn's disease (CD) is heterogeneous, with approximately 23%-46% of those achieving clinical remission after induction therapy experiencing secondary loss of response (SLR) within the first year. This significantly increases the risk of serious adverse outcomes. In this study, we developed a delta-radiomics model based on longitudinal changes in visceral adipose tissue assessed through computed tomography enterography. This model further integrates clinical and imaging biomarkers to identify patients with CD at high risk of SLR. This non-invasive approach holds promise as a valuable tool for optimizing personalized treatment regimens and guiding monitoring strategies. |
| Publish Date |
2025-06-06 03:09 |
| Citation |
<p>Li X, Song FL, He HF, Zeng SM, Feng ZC, Rong PF. Longitudinal computed tomography-based delta-radiomics of visceral adipose tissue predicts infliximab secondary loss of response in Crohn’s disease patients. <i>World J Gastroenterol</i> 2025; 31(21): 105895</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i21/105895.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i21.105895 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
