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6/11/2025 6:21:37 AM | Browse: 9 | Download: 84
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 105904
Country Pakistan
Received
2025-02-10 08:10
Peer-Review Started
2025-02-14 01:54
To Make the First Decision
Return for Revision
2025-03-14 10:00
Revised
2025-03-21 08:48
Second Decision
2025-04-07 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-07 11:01
Articles in Press
2025-04-07 11:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-04-11 05:19
Typeset the Manuscript
2025-06-04 01:58
Publish the Manuscript Online
2025-06-11 06:21
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Pancreatohepatobiliary neuroendocrine tumors diagnosed through endoscopic ultrasound: Clinical characteristics and factors associated with high-grade lesions
Manuscript Source Invited Manuscript
All Author List Abbas A Tasneem, Nasir H Luck and Muhammed Mubarak
ORCID
Author(s) ORCID Number
Abbas A Tasneem http://orcid.org/0000-0002-9964-0977
Nasir H Luck http://orcid.org/0000-0002-4752-4157
Muhammed Mubarak http://orcid.org/0000-0001-6120-5884
Funding Agency and Grant Number
Corresponding Author Muhammed Mubarak, Professor, Department of Histopathology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Key Words Neuroendocrine tumors; Pancreatohepatobiliary; Endoscopic ultrasound; Clinical characteristics
Core Tip Pancreatohepatobiliary neuroendocrine tumors (PHB-NETs) are now mostly diagnosed via endoscopic ultrasound (EUS), with the pancreas being the most frequent site. While most PHB-NETs are benign, one-third are high-grade neuroendocrine cancers (NECs). Insulinomas are the predominant functioning neuroendocrine tumors. Key risk factors for NECs include age > 40 years, extra-pancreatic origin and small-cell histology. EUS-guided biopsy is essential for early detection, risk stratification, and treatment planning of PHB-NETs. Clinicians should maintain a high index of suspicion for NECs in older patients with non-pancreatic lesions and small-cell histology to optimize management strategies.
Publish Date 2025-06-11 06:21
Citation <p>Tasneem AA, Luck NH, Mubarak M. Pancreatohepatobiliary neuroendocrine tumors diagnosed through endoscopic ultrasound: Clinical characteristics and factors associated with high-grade lesions. <i>World J Gastrointest Endosc</i> 2025; 17(6): 105904</p>
URL https://www.wjgnet.com/1948-5190/full/v17/i6/105904.htm
DOI https://dx.doi.org/10.4253/wjge.v17.i6.105904
Full Article (PDF) WJGE-17-105904-with-cover.pdf
STROBE Statement 105904-STROBE-statement.pdf
Manuscript File 105904_Auto_Edited_062527.docx
Answering Reviewers 105904-answering-reviewers.pdf
Audio Core Tip 105904-audio.opus
Biostatistics Review Certificate 105904-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105904-conflict-of-interest-statement.pdf
Copyright License Agreement 105904-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 105904-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105904-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105904-non-native-speakers.pdf
Peer-review Report 105904-peer-reviews.pdf
Scientific Editor Work List 105904-scientific-editor-work-list.pdf
CrossCheck Report 105904-crosscheck-report.pdf