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11/19/2025 5:58:08 AM | Browse: 2 | Download: 5
Publication Name World Journal of Transplantation
Manuscript ID 105905
Country France
Received
2025-02-21 03:39
Peer-Review Started
2025-02-21 03:39
To Make the First Decision
Return for Revision
2025-03-25 05:20
Revised
2025-04-24 07:20
Second Decision
2025-09-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-24 09:50
Articles in Press
2025-09-24 09:50
Publication Fee Transferred
2025-06-11 21:01
Edit the Manuscript by Language Editor
2025-09-29 18:53
Typeset the Manuscript
2025-10-22 02:52
Publish the Manuscript Online
2025-11-19 05:58
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Case Report
Article Title Toxic agranulocytosis following nitazoxanide treatment for norovirus diarrhea in a kidney transplant recipient: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Dorian Grépilloux, Corentin Guéneau, Jules Weinhard, Rémi Richaud, Eloi Chevallier, Thomas Jouve, Julien Dusserre and Lionel Rostaing
ORCID
Author(s) ORCID Number
Lionel Rostaing http://orcid.org/0000-0002-5130-7286
Funding Agency and Grant Number
Corresponding Author Lionel Rostaing, MD, PhD, Professor, Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation, Grenoble University Hospital, CS10217, Grenoble 38043, France. lrostaing@chu-grenoble.fr
Key Words Agranulocytosis; Neutropenia; Nitazoxanide; Norovirus; Iatrogeny; Case report
Core Tip Nitazoxanide is a thiazolide compound. The Food and Drug Administration has approved it for the treatment of Giardia intestinalis and Cryptosporidium parvum infections in immunocompromised patients aged 12 years or older. In immunocompromised patients, nitazoxanide use for chronic Norovirus diarrhea has been reported and appears promising, including in solid organ transplant recipients. However, the drug is not yet approved for this indication. We herein report on a patient for which nitazoxanide induced dose-dependent toxic agranulocytosis.
Publish Date 2025-11-19 05:58
Citation <p>Grépilloux D, Guéneau C, Weinhard J, Richaud R, Chevallier E, Jouve T, Dusserre J, Rostaing L. Toxic agranulocytosis following nitazoxanide treatment for norovirus diarrhea in a kidney transplant recipient: A case report and review of literature. <i>World J Transplant</i> 2025; 15(4): 105905</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i4/105905.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i4.105905
Full Article (PDF) WJT-15-105905-with-cover.pdf
CARE Checklist–2016 105905-CARE-Checklist-2016.pdf
Manuscript File 105905_Auto_Edited_020414.docx
Answering Reviewers 105905-answering-reviewers.pdf
Audio Core Tip 105905-audio.mp3
Conflict-of-Interest Disclosure Form 105905-conflict-of-interest-statement.pdf
Copyright License Agreement 105905-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 105905-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 105905-non-native-speakers.pdf
Peer-review Report 105905-peer-reviews.pdf
Scientific Misconduct Check 105905-scientific-misconduct-check.png
Scientific Editor Work List 105905-scientific-editor-work-list.pdf
CrossCheck Report 105905-crosscheck-report.pdf