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Articles Published Processes
9/15/2025 8:38:05 AM | Browse: 121 | Download: 1
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Received |
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2025-02-11 05:09 |
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Peer-Review Started |
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2025-02-11 05:09 |
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To Make the First Decision |
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Return for Revision |
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2025-03-13 09:34 |
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Revised |
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2025-03-31 08:34 |
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Second Decision |
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2025-08-12 02:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-12 06:46 |
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Articles in Press |
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2025-08-12 06:46 |
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Publication Fee Transferred |
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2025-04-15 01:05 |
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Edit the Manuscript by Language Editor |
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2025-08-14 01:40 |
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Typeset the Manuscript |
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2025-09-01 08:23 |
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Publish the Manuscript Online |
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2025-09-15 08:38 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Correlation between KAT6A and PD-L1 expression, as well as assessed the impact of KAT6A on the colorectal cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Zhen-Dong Zhou, Jian-Pei Zhao, Shu-Chun Zheng and Ting-Ting Wang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ting-Ting Wang, Department of General Medicine, Ningbo No. 2 Hosptial, No. 41 Xibei Street, Ningbo 315000, Zhejiang Province, China. 13606584845@163.com |
Key Words |
Colorectal cancer; Epigenetic regulation; KAT6A; PD-L1; Immune evasion |
Core Tip |
KAT6A drives colorectal cancer (CRC) progression and immune evasion by promoting histone H3 propionylation to epigenetically activate PD-L1 expression. Targeting KAT6A or its downstream H3K23pr-PD-L1 axis represents a promising therapeutic strategy to overcome Immune checkpoint inhibitors resistance in CRC. |
Publish Date |
2025-09-15 08:38 |
Citation |
<p>Zhou ZD, Zhao JP, Zheng SC, Wang TT. Correlation between KAT6A and PD-L1 expression, as well as assessed the impact of KAT6A on the colorectal cancer. <i>World J Gastrointest Oncol</i> 2025; 17(9): 105937</p> |
URL |
https://www.wjgnet.com/1948-5204/full/v17/i9/105937.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v17.i9.105937 |
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