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9/15/2025 8:38:05 AM | Browse: 121 | Download: 1
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 105937
Country China
Received
2025-02-11 05:09
Peer-Review Started
2025-02-11 05:09
To Make the First Decision
Return for Revision
2025-03-13 09:34
Revised
2025-03-31 08:34
Second Decision
2025-08-12 02:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-12 06:46
Articles in Press
2025-08-12 06:46
Publication Fee Transferred
2025-04-15 01:05
Edit the Manuscript by Language Editor
2025-08-14 01:40
Typeset the Manuscript
2025-09-01 08:23
Publish the Manuscript Online
2025-09-15 08:38
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Correlation between KAT6A and PD-L1 expression, as well as assessed the impact of KAT6A on the colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Zhen-Dong Zhou, Jian-Pei Zhao, Shu-Chun Zheng and Ting-Ting Wang
ORCID
Author(s) ORCID Number
Zhen-Dong Zhou http://orcid.org/0009-0005-0820-9014
Ting-Ting Wang http://orcid.org/0009-0001-9944-2698
Funding Agency and Grant Number
Corresponding Author Ting-Ting Wang, Department of General Medicine, Ningbo No. 2 Hosptial, No. 41 Xibei Street, Ningbo 315000, Zhejiang Province, China. 13606584845@163.com
Key Words Colorectal cancer; Epigenetic regulation; KAT6A; PD-L1; Immune evasion
Core Tip KAT6A drives colorectal cancer (CRC) progression and immune evasion by promoting histone H3 propionylation to epigenetically activate PD-L1 expression. Targeting KAT6A or its downstream H3K23pr-PD-L1 axis represents a promising therapeutic strategy to overcome Immune checkpoint inhibitors resistance in CRC.
Publish Date 2025-09-15 08:38
Citation <p>Zhou ZD, Zhao JP, Zheng SC, Wang TT. Correlation between KAT6A and PD-L1 expression, as well as assessed the impact of KAT6A on the colorectal cancer. <i>World J Gastrointest Oncol</i> 2025; 17(9): 105937</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i9/105937.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i9.105937
Full Article (PDF) WJGO-17-105937-with-cover.pdf
Manuscript File 105937_Auto_Edited_045454.docx
Answering Reviewers 105937-answering-reviewers.pdf
Audio Core Tip 105937-audio.mp3
Biostatistics Review Certificate 105937-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105937-conflict-of-interest-statement.pdf
Copyright License Agreement 105937-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 105937-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 105937-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105937-non-native-speakers.pdf
Peer-review Report 105937-peer-reviews.pdf
Scientific Misconduct Check 105937-scientific-misconduct-check.png
Scientific Editor Work List 105937-scientific-editor-work-list.pdf
CrossCheck Report 105937-crosscheck-report.pdf